Browsing by Subject "Free radical scavenging"

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    Composition, antioxidant, antimicrobial and enzyme inhibition activities of two Origanum vulgare subspecies (subsp. vulgare and subsp. hirtum) essential oils
    (Elsevier B.V., 2015) Sarikurkcu C.; Zengin G.; Oskay M.; Uysal S.; Ceylan R.; Aktumsek A.
    Essential oils (EOs) from Origanum vulgare subsp. vulgare (OVV) and O. vulgare subsp. hirtum (OVH) were evaluated for antioxidant activities (DPPH, ABTS, FRAP, CUPRAC, β-carotene/linoleic acid, phosphomolybdenum and metal chelating), antimicrobial and inhibitory properties against acetylcholinesterase, butrylcholinesterase, tyrosinase, α-amylase and α-glucosidase. Thymol and linalool were identified as major component in OVV and OVH essential oils, respectively. O. vulgare subsp. vulgare exhibited a strong free radical scavenging, reducing power, antimicrobial and acetylcholinesterase, butrylcholinesterase, α-amylase and α-glucosidase inhibitory activity. Interestingly, OVH possess a significant metal chelating and tyrosinase inhibitory activities. The EOs of both species exhibited moderate antibacterial and antifungal activities. The MIC values of the EOs ranged from 85.3 to 426.7. μg/mL. O. vulgare subsp. vulgare showed higher activity against Sarcina lutea with the lowest MIC (85.3. μg/mL), whereas OVH indicated strong activity for Candida albicans with MIC value of 85.3. μg/mL. The data suggest that the Origanum EOs could be used as valuable new natural agents with functional properties for food and pharmacology industries. © 2015 Elsevier B.V.
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    A comprehensive study on chemical composition, antioxidant and enzyme inhibition activities of the essential oils of Chenopodium botrys collected from three different parts of Turkey
    (Elsevier B.V., 2017) Ozer M.S.; Sarikurkcu C.; Ceylan O.; Akdeniz I.; Tepe B.
    In this study, we aimed to evaluate the chemical composition of the essential oil of Chenopodium botrys L. collected from three different parts of Turkey. Additionally, we analyzed the antioxidant activities of the oil samples by using free radical scavenging, phosphomolybdenum, ferrous ion chelating, and reducing power assays as well as their inhibitory activities on acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and tyrosinase. According to the results of GC-FID and GC–MS analyses, twenty-seven, twenty-four, and sixteen compounds were identified representing 94.45%, 96.96%, and 94.41% of the oils, respectively. In Afyonkarahisar and Isparta samples, ledol (25.11% and 22.73%), elemol (15.25% and 24.86%), and germacrene D-4-ol (14.83% and 11.27%) were determined as the major compounds, whereas ledol (31.83%), elemol (23.70%), and eudesm-7(11)-en-4-ol (8.94%) were found as the main compounds of Konya sample. The oil of Isparta sample showed the maximum radical scavenging activity in all test systems, except superoxide anion radical scavenging assay. Phosphomolybdenum, ferrous ion chelating, and reducing power assays were resulted in the superiority of Afyonkarahisar sample. In AChE and tyrosinase inhibition assays, the essential oil of C. botrys collected from Konya showed the maximum activity (0.87 mg GALAEs/g oil and 0.82 mg KAEs/g oil, respectively). On the other hand, BChE inhibition assay was resulted in the superiority of Afyonkarahisar sample (1.02 mg GALAEs/g oil). In order to determine the contribution of oil components to the biological activity, correlation coefficients between the compounds and assays were also presented. © 2017