Browsing by Subject "Glaucoma"

Now showing 1 - 6 of 6
  • No Thumbnail Available
    Item
    Ophthalmic findings in GAPO syndrome
    (1999) Ilker S.S.; Öztürk F.; Kurt E.; Temel M.; Gül D.; Sayli B.S.
    Background: The main manifestations of GAPO syndrome are growth retardation (G), alopecia (A), pseudoanodontia (P), and optic atrophy (O). Cases: This syndrome has been described in 21 patients from 16 different families. Four cases are from Turkey and have been presented by Sayli and Gul. The purpose of our study is to document the cases from Turkey and discuss the ophthalmological and neuro-ophthalmolgical findings of these and other reported GAPO cases. Observations: All patients in the literature and our 4 cases have severe growth retardation with delayed bone age in infancy, characteristic facial appearance (high and bossed forehead, midface hypoplasia), alopecia or severe hypotrichosis, and pseudoanodontia. Optic atrophy was present in 1 of our cases and in 5 previous cases. Glaucoma was present in 5 cases, including 2 of ours. Buphthalmia and keratopathy secondary to glaucoma were also observed. White eyelashes, seen only in our cases, may be a sign of 'early senility.' Conclusions: Optic atrophy is not a constant finding in GAPO syndrome. Glaucoma may accompany the ocular findings. This syndrome has been attributed to either ectodermal dysplasia or the accumulation of extracellular connective tissue matrix, due to an enzyme deficiency involved in its metabolism. Current studies show that an elastin defect and secondary changes in collagen may be important in the pathogenesis of the disease.
  • No Thumbnail Available
    Item
    Trabeculectomy for advanced glaucoma.
    (2011) Baser E.F.; Seymenoglu G.; Mayali H.
    The objective of this study is to evaluate the visual prognosis and postoperative course in advanced glaucoma patients who underwent trabeculectomy. The records of 30 patients with advanced visual field (VF) defects undergoing trabeculectomy were retrospectively reviewed. Severe VF defects were defined as those with a sensitivity of ≤5 dB either in more than 85% of test points, excluding the central four points, or in >75% of test points, including three of the central four points with threshold automated perimetry. Main outcome measures were intraocular pressure (IOP), corrected visual acuity (VA) and mean deviation (MD) of VF tests. Mean preoperative IOP, VA and MD values were compared with their respective postoperative values. The latest examination of each patient was used to determine postoperative outcome measures. In addition, any complications encountered were recorded. A total of 34 trabeculectomies were performed. The mean age was 59.3 years (13-80 years). The mean follow-up time was 41.1 months (3-120 months). Preoperatively the mean IOP was 28.4 ± 13.1 mmHg, and the mean postoperative IOP was 14.8 ± 5.0 mmHg (P = 0.001). Preoperatively the mean VA was 0.87 ± 80, and the mean value of the MD was -24.5 ± 6.7 dB. At the latest follow-up there was no significant difference in VA (0.89 ± 79, P = 0.699) and MD (-23.9 ± 6.7, P = 0.244) values. Transient hypotony occured in five eyes while one eye with mitomycin C trabeculectomy experienced extended hypotony. Ten eyes showed reduction of VA between 1 and 5 lines due to cataracts and five eyes had late bleb failure with uncontrolled IOP. One patient had late endophthalmitis and one patient presented with blebitis, both of which were successfully treated. No patients experienced wipe-out phenomenon. In conclusion, our study of advanced glaucoma patients undergoing trabeculectomy, vision was preserved with no cases of unexplained loss of central vision. IOP was largely controllable, with cataract being the leading factor decreasing VA at late term.
  • No Thumbnail Available
    Item
    Congenital iris ectropion associated with juvenile glaucoma
    (2011) Seymenoǧlu G.; Başer E.
    Congenital iris ectropion is an uncommon malformation of the anterior segment of the eye. The authors describe a case of bilateral congenital iris ectropion associated with juvenile glaucoma in an otherwise healthy 9-year-old girl. Intra-ocular pressure (IOP) measured by Goldmann applanation tonometry was 40 mmHg in the right eye and 32 mmHg in the left eye. Despite maximum IOP lowering therapy, the desired IOP levels needed to prevent further progression of the glaucoma could not be achieved. Visual field testing and confocal scanning laser tomography showed glaucomatous neuropathy. Trabeculectomy with antimetabolites (mitomycin C 0.2 mg/ml) was performed in both eyes and IOP was normalized without IOP lowering medications during a follow-up of 4 years. The authors point out the importance of recognizing congenital iris ectropion early to prevent blindness in young patients and improve their prognosis. © 2010 Springer Science+Business Media B.V.
  • No Thumbnail Available
    Item
    Comparison of spectral-domain optical coherence tomography and heidelberg retina tomograph III optic nerve head parameters in glaucoma
    (2013) Seymenoǧlu G.; Başer E.; Öztürk B.
    Background: To evaluate the agreement between the optic nerve head (ONH) measurements obtained by spectral-domain optical coherence tomography/scanning laser ophthalmoscope (SD-OCT/SLO) and the Heidelberg retinal tomograph III (HRT-III), and to compare the ONH measurements of both devices in different glaucoma types. Methods: In a prospective study, 30 patients with primary open-angle glaucoma (POAG) and 30 patients with pseudoexfoliation glaucoma (PXG) were enrolled. All patients underwent SD-OCT/SLO and HRT-III evaluation of the ONH during the same visit. Agreement between measurements of SD-OCT/SLO and HRT-III were evaluated by determination of intraclass correlation coeficients. In addition, mean ONH measurements obtained with both devices were compared between POAG and PXG patient groups. Results: Mean SD-OCT/SLO measurements were greater than those of HRT-III, except for mean and maximum cup depth. Intraclass correlation coefficient values for disc area, rim area, cup area, cup/disc area ratio, mean cup depth and maximum cup depth were 0.367, 0.213, 0.632, 0.681, 0.775 and 0.661, respectively. No significant differences were found between ONH parameters of POAG and PXG patients as measured with both devices (p > 0.01). Conclusion: ONH measurements with SD-OCT/SLO and HRT-III did not show clinically acceptable agreement in glaucoma patients. This precludes interchangeable use of these measurements in clinical practice. PXG and POAG patient groups displayed similar ONH measurements with both devices. Copyright © 2012 S. Karger AG, Basel.
  • No Thumbnail Available
    Item
    Comparison of icare pro tonometry and icare one tonometry measurements in healthy eyes
    (Turkish Ophthalmology Society, 2019) Mayalı H.; Sarıgül Ç.; Kurt E.; Kayıkçıoğlu Ö.R.; İlker S.S.
    Objectives: To compare intraocular pressure (IOP) measurements obtained with the Icare Pro tonometer used in clinical practice and the Icare One self-tonometer. Materials and Methods: Fifty-two eyes of 52 healthy, right-handed individuals with no prior intraocular surgery or ocular trauma, structural ocular pathology, or systemic disease were evaluated. IOP was first measured using the Icare Pro tonometer. The participants were then told how to use the Icare One tonometer and asked to measure their own IOP. The results were analyzed statistically using SPSS v.24. Results: Of the 52 healthy participants, 16 (30.7%) were male and 36 (69.3%) were female. Their mean age was 31.6±6.3 (23-47) years. Mean IOP measured with the Icare Pro was 17.10±6.2 (11.5-25.2) mmHg, and the mean self-measured IOP with Icare One was 14.01±3.4 (7-24) mmHg. When the two methods were compared using Levene’s t-test, there was a significant mean difference of -3.08±0.6 (95% confidence interval: -4.39 -1.78; p<0.001). Conclusion: In this study, there was a significant difference between the IOP measurements we made using the Icare Pro and the participants’ self-measured IOP using the Icare One, with the latter being relatively lower. This may be related to the fact that the participants were unfamiliar with using the Icare One. Although the Icare One is a promising tool for glaucoma patients to self-monitor their IOP, further studies are needed. © 2019 by Turkish Ophthalmological Association.
  • No Thumbnail Available
    Item
    Evaluation of the effect of body position on intraocular pressure measured with rebound tonometer
    (Turkish Ophthalmology Society, 2019) Mayalı H.; Tekin B.; Kayıkçıoğlu Ö.R.; Kurt E.; İlker S.S.
    Objectives: It is important to determine variables that influence intraocular pressure (IOP) measurement. This study aimed to evaluate the effect of body position on IOP. Materials and Methods: The study included 52 right eyes of 52 patients who presented to the ophthalmology department of our hospital and had no ocular disease except refractive errors. IOP was measured with an Icare PRO tonometer while patients were in sitting, standing, and supine positions, with intervals of 10 minutes between the positions. Correlations between the results were evaluated using Spearman’s correlation analysis and Wilcoxon tests. Results: Thirty-six of the 52 patients were female, 16 were male. Mean age was 31.65±6.30 (23-47) years. Mean IOP values in the sitting, standing, and lying positions were 17.76±3.41 (12.70-25.60) mmHg, 17.10±3.27 (11.50-25.20) mmHg, and 18.46±4.67 (10.50-29.40) mmHg, respectively. There were no statistically significant differences between measurements taken in the different positions (p=0.112, p=0.472, p=0.071). We observed that there was no relationship between age and body position (p>0.45, p>0.79, p>0.77) or between gender and position (p>0.59, p>0.69, p>0.54). Conclusion: Gender and age had no effect on IOP measured in different body positions. There were also no significant differences between IOP values measured in the different positions. Therefore, we believe the portable Icare PRO tonometer can be used for patients who are confined to bed and will provide IOP measurements that are concordant with values obtained while sitting. © 2019 by Turkish Ophthalmological Association.