Browsing by Subject "Human respiratory syncytial virus"

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    Outcome of the Respiratory Syncytial Virus related acute lower respiratory tract infection among hospitalized newborns: A prospective multicenter study
    (Taylor and Francis Ltd, 2016) Alan S.; Erdeve O.; Cakir U.; Akduman H.; Zenciroglu A.; Akcakus M.; Tunc T.; Gokmen Z.; Ates C.; Atasay B.; Arsan S.; Anik A.; Turkmen M.K.; Erdogan Y.; Oygur N.; Kahvecioglu D.; Yildiz D.; Caner I.; Tekgunduz K.S.; Kurt A.; Yigit Y.; Bilgili G.; Bolat F.; Cevit O.; Ozlu F.; Satar M.; Ertugrul S.; Cakir B.; Unal S.; Iscan B.; Duman N.; Ergor S.N.; Yalaz M.; Celik I.; Celik U.; Hirfanoglu I.M.; Koc E.; Sivasli E.; Melekoglu N.A.; Kiray Bas E.; Bozkaya D.; Korkmaz A.; Ozdemir R.; Karadag A.; Ozer E.; Ilhan O.; Mutlu M.; Aslan Y.; Erener- Ercan T.; Cetinkaya M.; Sahin O.; Akin M.A.; Okumus N.; Demirel G.; Kilic A.; Turkoglu-Unal E.; Bulbul A.; Takci S.; Anuk-Ince D.; Ciftdemir N.A.; Acunas B.; Ozkan H.; Koksal N.; Okulu E.; Demir N.; Tuncer O.; Dizdar E.A.; Oguz S.; Dilmen U.
    Aim: To determine the incidence and outcomes of respiratory syncytial virus (RSV)-related acute lower respiratory tract infection (ALRI) including morbidity, nosocomial infection and mortality among newborn infants who were admitted to the neonatal intensive care units (NICUs).Methods: A multicenter, prospective study was conducted in newborns who were hospitalized with community acquired or nosocomial RSV infection in 44 NICUs throughout Turkey. Newborns with ALRI were screened for RSV infection by Respi-Strip®-test. Main outcome measures were the incidence of RSV-associated admissions in the NICUs and morbidity, mortality and epidemics results related to these admissions.Findings: The incidence of RSV infection was 1.24% (n: 250) and RSV infection constituted 19.6% of all ALRI hospitalizations, 226 newborns (90.4%) had community-acquired whereas 24 (9.6%) patients had nosocomial RSV infection in the NICUs. Of the 250 newborns, 171 (68.4%) were full-term infants, 183 (73.2%) had a BW >2500 g. RSV-related mortality rate was 1.2%. Four NICUs reported seven outbreaks on different months, which could be eliminated by palivizumab prophylaxis in one NICU.Conclusion: RSV-associated ALRI both in preterm and term infants accounts an important percent of hospitalizations in the season, and may threat other high-risk patients in the NICU. © 2015 Taylor & Francis.
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    Pediatric pulmonology year in review 2016: Part 2
    (John Wiley and Sons Inc., 2017) Auten R.; Ren C.; Yilmaz O.; Noah T.L.
    Pediatric Pulmonology continues to publish research and clinical topics related to the entire range of children's respiratory disorders. As we have done annually in recent years, we here summarize some of the past year's publications in our major topic areas, as well as selected literature in these areas from other core journals relevant to our discipline. This review (Part 2) covers selected articles on neonatology, asthma, physiology and lung function testing, and infectious diseases. © 2017 Wiley Periodicals, Inc.
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    Does atopy affect the course of viral pneumonia?
    (Elsevier Doyma, 2018) Erdem S.B.; Can D.; Girit S.; Çatal F.; Şen V.; Pekcan S.; Yüksel H.; Bingöl A.; Bostancı I.; Erge D.; Ersu R.
    Background: The presence of atopy is considered as a risk factor for severe respiratory symptoms in children. The objective of this study was to examine the effect of atopy on the course of disease in children hospitalised with viral pneumonia. Methods: Children between the ages of 1 and 6 years hospitalised due to viral pneumonia between the years of 2013 and 2016 were included to this multicentre study. Patients were classified into two groups as mild–moderate and severe according to the course of pneumonia. Presence of atopy was evaluated with skin prick tests. Groups were compared to evaluate the risk factors associated with severe viral pneumonia. Results: A total of 280 patients from nine centres were included in the study. Of these patients, 163 (58.2%) were male. Respiratory syncytial virus (29.7%), Influenza A (20.5%), rhinovirus (18.9%), adenovirus (10%), human metapneumovirus (8%), parainfluenza (5.2%), coronavirus (6%), and bocavirus (1.6%) were isolated from respiratory samples. Eighty-five (30.4%) children had severe pneumonia. Atopic sensitisation was found in 21.4% of the patients. Ever wheezing (RR: 1.6, 95% CI: 1.1–2.4), parental asthma (RR: 1.5, 95% CI: 1.1–2.2), other allergic diseases in the family (RR: 1.8, 95% CI: 1.2–2.9) and environmental tobacco smoke (RR: 1.6, 95% CI: 1.1–3.5) were more common in the severe pneumonia group. Conclusions: When patients with mild–moderate pneumonia were compared to patients with severe pneumonia, frequency of atopy was not different between the two groups. However, parental asthma, ever wheezing and environmental tobacco smoke exposure are risk factors for severe viral pneumonia in children. © 2017 SEICAP