Browsing by Subject "Oxidative stress"
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Item Multi-Biomarker Responses After Exposure to Pollution in the Mediterranean Mussels (Mytilus galloprovincialis L.) in the Aegean Coast of Turkey(Springer New York LLC, 2017) Ozkan D.; Dagdeviren M.; Katalay S.; Guner A.; Yavaşoğlu N.Ü.K.In this study, sublethal effects on the Mediterranean mussels (Mytilus galloprovincialis L.) collected from the Aegean coast of Turkey were determined. Enzymes such as glutathione-S-transferase (GST), superoxide dismutase (SOD), catalase (CAT), and acetylcholinesterase (AChE), metallothionein (MT) mRNA expressions, thiobarbituric acid reactive substances (TBARS) contents, determination of 14 heavy metals and micronucleus frequency were selected as multibiomarkers. Results show that heavy metals and an increase in the level of MT gene expression have been determined in tissues of mussels collected from all stations. The GST, SOD and CAT enzymes were increased in mussels of Aliaga and Old Foca, compared to the mussels of Urla, while it was showed inhibition at AChE levels. Extensive LP is determined on mussels of Aliaga. It was determined that mussels in Aliaga region have exposed more oxidative stress than Old Foca and Urla. These biomarkers were carried out for the first time in these stations to assess environmental quality. © 2016, Springer Science+Business Media New York.Item Effects of electromagnetic fields application on experimental varicocele model in rats; [Sicanlarda Deneysel Varikosel Modelinde Elektromanyetik Alan Uygulamalarinin Etki](Institute of Electrical and Electronics Engineers Inc., 2017) Gulbagca F.; Sal D.H.; Saygili S.; Sonmez P.K.; Aydemir I.; Ozkut M.; Ozturk S.; Gumusay M.; Kaya A.; Tuglu M.I.Varicocele is the most clinical condition which can be treated by surgery. The frequency in male is 20%. The half of infertile patient has this pathology which there is dilatation in plexus pampiniformis veins of testes. Varicocele causes increase of heat or increse of oxidative stres in seminifer tubules where they produce pathology for spermatogenesis. Low frequency magnetic fields are useful for the treatment of many area where they become important role. In this study the effect of low frequency magnetic fields on the experimental varicocele model of rat testes was investigated. The parameters for oxidative stres suggest eNOS and iNOS with apoptosis were evaluated by immunohistochemical staining. There was increaese in eNOS, iNOS and apoptosis by the varicocele experiment where there was testicular damage and low frequency magnetic fields caused decrease in oxidative stress and apoptosis. Application of magnetic fields can help the clinical varicocele pathologies either with treatment or supportive effect. © 2016 IEEE.Item An investigation on the seasonal variations of the biomarkers of oxidative stress response and their correlations to Polonium-210 in mussel (Mytilus galloprovincialis) and common sole (Solea solea) from İzmir Bay, Turkey(Elsevier Ltd, 2018) Aslan E.; Uğur Görgün A.; Katalay S.; Filizok I.; Becerik S.; Aydemir T.It is well known that the marine organisms are used as biological indicators for environmental pollution studies. Among these studies, the research on oxidative stress has been increasing in recent years. In this study, mussels (Mytilus galloprovincialis) and fish (Solea solea) samples were collected seasonally from İnciraltı İzmir, Turkey. This station was in an area where fishing is carried out for human consumption. The relationship between 210Po and oxidative stress markers (lipid peroxidation (LPO), H2O2 and proline) was investigated in the mussel tissue (digestive gland, gills) and fish tissue (liver, gills) samples. The present study indicated that H2O2 accumulated with increasing 210Po concentration in mussel samples. Statistically significant correlation were found between H2O2 and 210Po and LPO and proline in mussel samples. This correlation between LPO and proline can be attributed to common environmental parameters (other than 210Po) affecting expression of both LPO and proline levels. There was not a significant correlation between 210Po and LPO levels. Similarly, a significant correlation was not found between 210Po and proline. © 2018 Elsevier Ltd