Browsing by Subject "Pigmentation Disorders"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
Item Nail changes in connective tissue diseases: Do nail changes provide clues for the diagnosis?(2007) Tunc S.E.; Ertam I.; Pirildar T.; Turk T.; Ozturk M.; Doganavsargil E.Objective: To evaluate the frequency and the specificity of nail changes associated with connective tissue diseases (CTD). Methods: In a case-control study, 190 patients including those with systemic lupus erythematosus (SLE; 56), rheumatoid arthritis (RA, 47), primary Sjögren's syndrome (pSS; 35), systemic sclerosis (SSc; 39), and dermatomyositis/polymyositis (DM/PM; 13) were enrolled in the study. Patients with SLE and other CTDs were compared with two different control groups. Twenty nails were examined. Nail features were noted and classified. Nail samples were collected for mycological cultures. Results: In patients with SLE, erythema of proximal nailfold (P < 0.01), splinter haemorrhages in fingernails (P < 0.01), capillary loops in proximal nailfold (P < 0.05), periungual erythema (P < 0.05), and thin nail plates (P < 0.05) were more common than those in controls. Only splinter haemorrhages were associated with the disease activity. In patients with SSc and DM/PM, splinter haemorrhages (P < 0.05) and capillary loops in proximal nailfold (P < 0.01) in fingernails were common as well. Increase in longitudinal curvature (P < 0.001), transverse curvature (P < 0.01), and white dull colour in fingernails were other frequent findings in patients with SSc. Increase in transverse curvature was associated with the disease activity in SSc. In patients with RA, splinter haemorrhages (P < 0.05), red lunula (P < 0.05), and white dull colour (P < 0.05) in fingernails were frequent. The sensitivity values of all these changes were very low. However, their specificity values were found to be relatively high. Conclusion: Proximal nailfold is the most important site of affection in CTDs. These nail changes can be used in combination with highly sensitive diagnostic modalities to establish an accurate diagnosis. © 2007 The Authors Journal compilation © 2007 European Academy of Dermatology and Venereology.Item Effect of socio-demographic characteristics and clinical findings on the quality of life of patients with chronic venous insufficiency(SAGE Publications Ltd, 2017) Soydan E.; Yılmaz E.; Baydur H.Objective: This study was planned and implemented to evaluate the effect of socio-demographic characteristics and clinical findings on the quality of life of patients with chronic venous insufficiency. Methods: The sample of this cross-sectional study consisted of 163 patients that presented with the diagnosis of chronic venous insufficiency to the cardiovascular surgery clinic of an education and research hospital in the west of Turkey. The data were collected during face-to-face interviews using a personal information form, clinical, etiology, anatomy, pathophysiology classification, venous insufficiency epidemiological and economic study-quality of life/symptoms scales and the Short Form-36. Descriptive statistics as well as univariate and multivariate analyses were used to analyze the data. Results: The chronic venous insufficiency patients were found to have a low quality of life. Advanced age, higher body mass index, longer working times, being on regular medication, hypertension and presence of pigmentation according to the clinical, etiology, anatomy, pathophysiology classification were found to be associated with a reduced physical score in SF-36. Furthermore, longer weekly working hours and presence of pigmentation reduced the Venous Insufficiency Epidemiological and Economic Study-Quality of Life/Symptoms scores. Undertaking physical exercise at twice and more than twice a week increased the overall physical scores in SF-36. Conclusions: The results of the study showed that the quality of life of chronic venous insufficiency patients are affected by not only physical characteristics, working hours and physical activity but also presence of edema and pigmentation. © 2016, © The Author(s) 2016.Item Mycosis fungoides mimicking pigmented purpuric dermatosis(Blackwell Publishing Inc., 2020) Gökyayla E.; Çetinarslan T.; Temiz P.; Türel Ermertcan A.[No abstract available]