Browsing by Subject "Radioimmunoassay"

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    Serum testosterone, growth hormone, and insulin-like growth factor-1 levels, mental reaction time, and maximal aerobic exercise in sedentary and long-term physically trained elderly males
    (2004) Ari Z.; Kutlu N.; Uyanik B.S.; Taneli F.; Buyukyazi G.; Tavli T.
    The aim of the study was to investigate the effect of regular exercise on maximum oxygen uptake capacity (VO2max), reaction time (RT), testosterone (T), growth hormone (GH), insulin-like growth factor-I (IGF-1) in athletes compared to sedentary controls. VO2max RT, T, GH, and IGF-I levels were 31.2 ± 6.2 ml/min/kg, 106.7 ± 23.2 s, 8.3 ± 1. 3 ng/mL 1.6 ± 0.7 ng/mL, 106.5 ± 27.0 ng/mL in master athlete group and 18.8 ± 5.1 ml/min/kg, 148.3 ± 39.3 s, 5.4 ± 1.7 ng/mL, 0.8 ± 0.3 ng/mL, 90.2 ± 23.8 ng/mL in sedentary control group, respectively. The differences between regularly exercising males and the control group of sedentary males were found to be statistically significant. The results showed that long-term exercise decreased RT and increased VO 2max, T, and GH in elderly males; elevated serum T and GH levels may be advantageous for brain functions.
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    Advanced oxidation protein products, ferrous oxidation in xylenol orange, and malondialdehyde levels in thyroid cancer
    (2007) Kosova F.; Çetin B.; Akinci M.; Aslan S.; Ari Z.; Sepici A.; Altan N.; Çetin A.
    Aims and Background: The oxidation of protein plays an essential role in the pathogenesis of an important number of degenerative and cancer diseases, which is now widely recognized. The aim is to examine advanced oxidation protein products (AOPPs), lipid peroxidation products malondialdehyde (MDA), and ferrous oxidation in xylenol orange (FOX) in blood samples of papillary thyroid cancer patients compared with healthy controls to determine the oxidation status and the change after thyroidectomy. Methods: Thirty-five female thyroid cancer patients who underwent total thyroidectomy and 39 female control subjects were included into this study. Prethyroidectomy and postthyroidectomy, AOPP, FOX, and MDA levels were studied. Results: Prethyroidectomy AOPP, FOX, and MDA levels were significantly higher compared to control (P < .05). In postthyroidectomy AOPP, FOX, and MDA levels were significantly decreased compared with prethyroidectomy levels (P < .05). However, postthyroidectomy levels on the 20th day were still significantly higher, compared to control subjects (P < .05). Conclusion: In conclusion, all of AOPP, FOX, and MDA levels that are markers of protein oxidation and lipid hyperoxidation may induce thyroid cancer development and begin to decrease after thyroidectomy. © 2007 Society of Surgical Oncology.