Browsing by Subject "SUCCESS"

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    Impact of graft type on anatomical and functional outcome in type-I tympanoplasty
    (ROYAL BELGIAN SOC EAR, NOSE, THROAT, HEAD & NECK SURGERY) Celik, O; Eskiizmir, G; Ulkumen, B; Karaca, G
    Objective: There is a general opinion that cartilage grafting in type-1 tympanoplasty has better anatomical outcomes when compared with fascia and perichondrium. But, regarding functional outcomes, however, although the literature is mainly in agreement about acceptable hearing gains, there is an on-going dispute on this matter. The aim of this study was to evaluate anatomical and functional outcomes in type-I tympanoplasty according to grafting materials. Methods: In this study, 154 cases who had undergone type-I tympanoplasty over a period of nine years were enrolled and divided into three groups according to graft type: i.e., fascia, perichondrium and cartilage. Pure tone audiometry was reviewed pre-and post-operatively (one year after surgery) for functional outcomes. The average air-bone gap (ABG) and air-conduction gain (ACG) were also determined pre-and post-operatively for each case. Tympanic membrane perforation was documented in terms of involved percentage and site. Results: A significant difference in air conduction gain between cartilage and other grafts (perichondrium (p<0.001), fascia (p<0.001)) was found, while no difference was found between fascia and perichondrium (p=0.720). There was no significant difference between groups in terms of anatomical outcomes (p=0.615). Conclusions: The majority of relevant studies are retrospectively designed, leading to a graft selection bias, while the impact of the site and size of perforation, which may have a confounding effect, is not taken into account. In this study, graft selection bias was eliminated by determining the distribution of the perforation site and size on a group basis. A comparable anatomical, but decreased functional, outcome for cartilage grafting when compared with TMF and perichondrium was revealed.
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    A New Tool for Faster Construction of Marine Biotechnology Collaborative Networks
    (FRONTIERS MEDIA SA) Rotter, A; Gaudêncio, SP; Klun, K; Macher, JN; Thomas, OP; Deniz, I; Edwards, C; Grigalionyte-Bembic, E; Ljubesic, Z; Robbens, J; Varese, GC; Vasquez, MI
    The increasing and rapid development in technologies, infrastructures, computational power, data availability and information flow has enabled rapid scientific advances. These entail transdisciplinary collaborations that maximize sharing of data and knowledge and, consequently, results, and possible technology transfer. However, in emerging scientific fields it is sometimes difficult to provide all necessary expertise within existing collaborative circles. This is especially true for marine biotechnology that directly addresses global societal challenges. This article describes the creation of a platform dedicated to facilitating the formation of short or mid-term collaborative networks in marine biotechnology. This online platform (https://www.ocean4biotech.eu/map/) enables experts (researchers and members of the marine biotechnology community in general) to have the possibility to showcase their expertise with the aim of being integrated into new collaborations/consortia on the one hand, or to use it as a search tool to complement the expertise in planned/running collaborations, on the other. The platform was created within the Ocean4Biotech (European transdisciplinary networking platform for marine biotechnology) Action, funded under the framework of the European Cooperation in Science and Technology (COST). To build the platform, an inquiry was developed to identify experts in marine biotechnology and its adjunct fields, to define their expertise, to highlight their infrastructures and facilities and to pinpoint the main bottlenecks in this field. The inquiry was open to all experts in the broad field of marine biotechnology, including non-members of the consortium. The inquiry (https://ee.kobotoolbox.org/single/UKVsBNtD) remains open for insertion of additional expertise and the resulting interactive map can be used as a display and search tool for establishing new collaborations.
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    Feature selection for Turkish Crowdfunding projects with using filtering and wrapping methods
    (ELSEVIER) Kilinc, M; Aydin, C
    Crowdfunding (CF) platforms host an increasing number of projects, where financial support from backers plays a vital role in project realization. Unfortunately, CF projects have experienced a downward trend in success rates. To address this issue, it is crucial to identify the factors that influence success by analyzing project characteristics. In our study, we collected project data from Turkey's Fongogo CF platform, performed feature selection, and rigorously tested the results. We employed various methods such as Pearson correlation, mutual information statistics, chi-square, Fisher's score from filtering methods, and recursive feature elimination from wrapper methods to understand feature relationships. We proposed a cross-validated recursive feature elimination method for feature selection. The identified success factors were classified using diverse machine learning algorithms, with the Gradient Boosting algorithm achieving the highest result of 84.28%. The results obtained with wrapper methods highlight the potential of utilizing features in decision support processes to enhance CF success.