Browsing by Subject "Sleep Apnea Syndromes"
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Item Is there a vicious cycle between obstructive sleep apnea and laryngopharyngeal reflux disease?(2009) Eskiizmir G.; Kezirian E.Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder which is mainly characterized by the repetitive episodes of obstructive apneas and/or hypopneas. It is associated with daytime sleepiness, decrements in quality of life, cardiovascular and cerebrovascular diseases and endocrine disturbances. In addition, there is a high prevalence of gastric reflux (including both gastroesophageal reflux and laryngopharyngeal reflux diseases) in patients with OSA. However, the mechanism underlying this association has not been completely established. Herein, we hypothesize that there is a vicious cycle between OSA and laryngopharyngeal reflux disease. Increased respiratory efforts in OSA generate more-negative intrathoracic pressure, contributing to reflux of gastric contents, which in turn creates inflammation and sensory deficits in the laryngeal and pharyngeal tissues that contributes to progression of OSA through both inflammatory and neuromuscular pathways. © 2009 Elsevier Ltd.Item Prevalence of habitual snoring and symptoms of sleep-disordered breathing in adolescents(2009) Sogut A.; Yilmaz O.; Dinc G.; Yuksel H.Objective: Sleep-disordered breathing is an important public health problem in adolescents. The aim of this study was to investigate the prevalence and risk factors of habitual snoring and symptoms of sleep-disordered breathing in adolescents. Methods: A cross-sectional study was conducted with children from primary schools and high schools that the ages ranged from 12 to 17 years. Data were collected by physical examination and questionnaires filled in by parents regarding sleep habits and possible risk factors of snoring. According to answers, children were classified into three groups: non-snorers, occasional snorers, and habitual snorers. Results: The response rate was 79.2%; 1030 of 1300 questionnaires were fully completed and analyzed. The prevalence of habitual snoring was 4.0%. Habitual snorers had significantly more nighttime symptoms including observed apneas, difficulty breathing, restless sleep and mouth breathing during sleep compared to occasional and non-snorers. Prevalence of habitual snoring was increased in children who had had tonsillar hypertrophy, allergic rhinitis, and maternal smoking. Conclusion: We found the prevalence of habitual snoring to be 4.0% in adolescents from the province of Manisa, Turkey which is low compared to previous studies. Habitual snoring is an important problem in adolescents and habitual snorers had significantly more nighttime symptoms of sleep-disordered breathing compared to non-snorers. © 2009 Elsevier Ireland Ltd. All rights reserved.Item Reliability and validity of the Turkish version of the pediatric sleep questionnaire: A tool for prediction of sleep related breathing disorder; [Pediatrik uyku anketi türkçe formunun geçerlilik ve güvenilirliǧi: Uyku ile ilişkili solunum bozukluǧunun tahmininde bir araç](2011) Yüksel H.; Söǧüt A.; Yilmaz O.; Kutluay E.Use of a questionnaire that predicts the diagnosis and influence of sleep related breathing disorder (SRBD) may be a cost-effective method to aid in both diagnostic algorithm and therapy. Therefore, the aim of this study was to adapt Pediatric Sleep Questionnaire (PSQ) into Turkish and to test the validity and reliability of the Turkish questionnaire. Total of 111 children (59 male, 52 female) aged 2 to 17 years who had symptoms suggestive of SRBD were enrolled consecutively. Demographic characteristics such as age and gender of all children enrolled in the study were recorded. All parents were questioned about symptom severity, frequency and duration. Lastly, PSQ was administered to all parents. Mean age of the children enrolled in the study was 8.1 ± 3.4 years. Total PSQ score ranged between 0 and 0.95 and mean score was 0.35 ± 0.22. Comparison of total PSQ scores between children reporting different symptom frequencies demonstrated that PSQ score increased as the symptom frequency increased (p< 0.001).There was a significant difference of all PSQ scores among the groups (p< 0.05 for all).Total PSQ score for children that did not report snoring was 0.2 ± 0.5 wile that for the ones who snore throughout sleep was 3.8 ± 0.5 (p< 0.001). Cronbach's alpha values for all domains of PSQ were satisfactory. All items were significantly correlated with their corresponding scale. Turkish version of PSQ is a valid and reliable tool that may be used in the initial evaluation of Turkish children with symptoms suggestive of SRBD.Item The evaluation of pattern and quality of sleep in patients with chronic rhinosinusitis with nasal polyps(Elsevier Ireland Ltd, 2017) Uz U.; Günhan K.; Yılmaz H.; Ünlü H.Objective The goal of this study is to evaluate the impact of chronic rhinosinusitis with nasal polyps (CRSwNP) on sleep pattern and sleep quality before and after functional endoscopic sinus surgery using subjective and objective parameters. Methods Twenty-two patients with CRSwNP were evaluated. All subjects underwent assessment by nasal endoscopy, rhinomanometry and computed tomography. Sleep pattern and sleep quality were evaluated by Pittsburgh sleep quality index (PSQI) and polysomnography (PSG). All patients were reassessed 6 months after surgery. Results Nasal resistance decreased after the surgery (p < 0.001). Postoperative PSQI scores were significantly lower than preoperative scores (p < 0.001). The preoperative mean values of total apnea index and apnea-hypopnea index were 25.4 and 13.3, respectively. After surgery, the total apnea and apnea-hypopnea index had decreased significantly to 7.8 and 11.2, respectively (p = 0.009 and 0.019, respectively). Conclusion In patients with CRSwNP, functional endoscopic sinus surgery significantly ameliorates sleep pattern and sleep quality. CRSwNP may be a predisposing factor for sleep related respiratory disorders. © 2017 Elsevier B.V.Item Investigation of Sleep Breathing Disorders in Young Patients (Under 55 years) with Mild Stroke(W.B. Saunders, 2020) Kisabay Ak A.P.D.A.; Şeyma Sarıtaş S.D.A.; Batum S.D.M.; Göktalay A.P.D.T.; Horasan P.D.G.D.; Selcuki P.D.D.; Yilmaz P.D.H.Introduction: Many patients with stroke also have sleep breathing disorders (SBD), most of which is obstructive sleep apnea (OSA). Methods: Sixty patients with a history of stroke aged under 55 years were included in our study. The demographic characteristics (age at stroke, sex, body mass index) of the patients and etiology of stroke was evaluated according to the Trial of Org 10712 in Acute Stroke (TOAST) classification. The National Institute of Health Stroke Scale (NIHSS) and Modified Rankin Scale (MRS) were used to evaluate functionality. All patients underwent polysomnography (PSG) investigations. Findings: Based on PSG investigations, seven patients were normal, 10 had primary snoring, and 14 had mild, 11 had moderate, and 18 had severe OSA. The demographic characteristics did not differ significantly between the groups. No significant correlation was found between disease severity and NIHSS, MRS or TOAST classifications. Large artery atherosclerosis in the etiology, facial paralysis and dysarthria in the neurological examination, and brain stem involvement in the stroke location were observed to accumulate in the severe OSA group. When the anterior system, posterior system, and association of both were compared for vessel location, no significant difference was found regarding circulatory systems. Conclusions: It is considered that SBD has also a role in the etiology of stroke in patients aged under 55 years, and it should be taken into consideration as much as other risk factors. This is the first study to emphasize the importance of this topic in the literature. © 2020 Elsevier Inc.