Browsing by Subject "data collection method"
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Item Retinol and α-tocopherol concentrations in breast milk of Turkish lactating mothers under different socio-economic status(2008) Tokuşoǧlu Ö.; Tansuǧ N.; Akşit S.; Dinç G.; Kasirga E.; Özcan C.Retinol and α-tocopherol levels in breast milk of Turkish mothers under different socio-economic status were investigated. Mature milk samples were collected from 92 lactating mothers living in Izmir and in Manisa, cities of Turkey, who were at 60-90 days of the lactating period. Socio-economic, anthropometric, and dietary data were collected by means of a questionnaire. The body mass index was used to determine the nutritional status. The retinol and α-tocopherol contents of breast milk were determined by high-performance liquid chromatography; the concentration of α-tocopherol was 9.84 μg/ml whereas retinol levels were 81.5 μg/100 ml. The questionnaire survey was used to determine the level of these vitamins in the daily ration of the women. No significant differences were found in terms of milk retinol and α-tocopherol levels for the variables income, educational level and mothers' body mass index.Item Mortality-associated factors of candidemia: a multi-center prospective cohort in Turkey(Springer Science and Business Media Deutschland GmbH, 2022) Kutlu M.; Sayın-Kutlu S.; Alp-Çavuş S.; Öztürk Ş.B.; Taşbakan M.; Özhak B.; Kaya O.; Kutsoylu O.E.; Şenol-Akar Ş.; Turhan Ö.; Mermut G.; Ertuğrul B.; Pullukcu H.; Çetin Ç.B.; Avkan-Oğuz V.; Yapar N.; Yeşim-Metin D.; Ergin Ç.Candidemia may present as severe and life-threatening infections and is associated with a high mortality rate. This study aimed to evaluate the risk factors associated with 30-day mortality in patients with candidemia. A multi-center prospective observational study was conducted in seven university hospitals in six provinces in the western part of Turkey. Patient data were collected with a structured form between January 2018 and April 2019. In total, 425 episodes of candidemia were observed during the study period. Two hundred forty-one patients died within 30 days, and the 30-day crude mortality rate was 56.7%. Multivariable analysis found that SOFA score (OR: 1.28, CI: 1.154–1.420, p < 0.001), parenteral nutrition (OR: 3.9, CI: 1.752–8.810, p = 0.001), previous antibacterial treatment (OR: 9.32, CI: 1.634–53.744, p = 0.012), newly developed renal failure after candidemia (OR: 2.7, CI: 1.079–6.761, p = 0.034), and newly developed thrombocytopenia after candidemia (OR: 2.6, CI: 1. 057–6.439, p = 0.038) were significantly associated with 30-day mortality. Central venous catheter removal was the only factor protective against mortality (OR: 0.34, CI:0.147–0.768, p = 0.010) in multivariable analysis. Candidemia mortality is high in patients with high SOFA scores, those receiving TPN therapy, and those who previously received antibacterial therapy. Renal failure and thrombocytopenia developing after candidemia should be followed carefully in patients. Antifungal therapy and removing the central venous catheter are essential in the management of candidemia. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.