Browsing by Subject "general condition deterioration"

Now showing 1 - 3 of 3
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    Surgical treatment of aortic stenosis of subvalvular, valvular and supravalvular levels and patent ductus arteriosus in a single procedure
    (2010) Sirin B.H.; Iskesen I.; Kurdal A.T.; Kahraman N.
    The association between discrete subaortic stenosis and valvular-supravalvular aortic stenosis and other cardiac anomalies is a well known but rarely reported occurrence. The aim of our paper is to define the patient that has four cardiac problems and repaired all of them in a single procedure. 12 year old boy has 1- subvalvular discrete membrane, 2- bicuspid aortic valvular stenosis, 3- supravalvular aortic stenosis and 4- patent ductus arteriosus. All of the problems were repaired and the patient was discharged asymptomatically after successful relief of the obstruction.
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    Ewing's sarcoma metastasis into the breast
    (2012) Örgüç S.; Başara I.; Poçan T.; Özgüven A.A.; Özkol M.
    The metastasis of extramammary malignancies into the breast is very unusual. Lymphoma, malignant melanoma, and rhabdomyosarcoma are the most common tumors that metastasize into breast tissue. The histological spectrum of breast masses in children and adolescents is different from that of adults. Imaging findings are useful for performing a diagnosis, but in a patient with a known malignancy, any enlarging breast mass, even one with a benign radiological appearance, should be investigated with a biopsy. In this article, we present the imaging findings of a 12-year-old female patient with breast metastasis of Ewing's sarcoma. © Turkish Society of Radiology 2012.
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    The protective effect of metformin against the noise-induced hearing loss
    (Springer Verlag, 2018) Kesici G.G.; Öcal F.C.A.; Gürgen S.G.; Erdem Ş.R.; Öğüş E.; Erbek H.S.; Özlüoğlu L.N.
    Objective: To test the protective effect of metformin against noise-induced hearing loss. Methods: 24 rats were included in the study. The first group was exposed to noise only, the second group took metformin, the third group was exposed to noise and took metformin, and the fourth group was neither exposed to noise nor took metformin as control group. After measurement of baseline DPOAE and ABR of rats, the metformin group and the metformin + noise group received 300 mg/kg/day metformin via gavage for 10 days. On the 11th day, group 1 and group 3 were exposured to white noise at 105 dB SPL for 15 h. After noise exposure, DPOAE and ABR measurements of all rats were repeated on days 1st, 7th, and 21st. At the end of the study, all animals were sacrificed and cochlear tissues were separated for immunohistochemical assessments. Results: ABR threshold values and DPAOE measurements of groups 1 and 3 were deteriorated on the 1st day after noise, while deterioration in group 1 continued on 7th and 21st days, but normalized on 7th day in group 3. After immune staining, a significant immunoreaction was observed in the noise group, while the reaction in the noise + metformin group was close to the control group. Conclusion: Metformin has a protective effect on noise-induced hearing loss in rats. As a conclusion, it is determined that metformin protects from permanent threshold shift in rats. It can be considered a good alternative for protecting noise-induced hearing loss. © 2018, Springer-Verlag GmbH Germany, part of Springer Nature.