Browsing by Subject "incontinence"

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    Evaluation of female athlete triad and gynecological complaints in young Turkish female athletes
    (S.O.G. CANADA Inc., 2016) Solmaz Hasdemir P.; Oral O.; Calik E.; Ulusoy M.; Varol R.; Tayfun Ozcakir H.
    Purpose: Female athlete triad (FAT) is a serious healthcare concern in the young female population. The aim of this study was to determine the prevalence and clinical characteristics of FAT and its relationship with gynecologic complaints of young Turkish female athletes. Materials and Methods: This was a cross-sectional survey and included 87 female athletes involved in a variety of sports as a case group and 85 sedentary female university students from Ege and Celal Bayar Universities. All subjects completed a questionnaire consisting of 32 separate questions assessing eating behavior, menstrual status, gynecologic and systemic complaints, psychological problems, and sexual history. SPSS 21.0 was used for statistical analysis. Results: This survey involved 172 females in between to 30 years of age. The age of menarche was found to be significantly lower in the sedentary group (p = 0.00). Late menstruation and oligo-amenorrhea were notable complaints among the athletes, and body mass index (BMI) was found to be statistically lower in the athletic group (p = 0.00). Cold hands and hair loss were seen more often in the sedentary group compared to the athletic group (p < 0.05). According to a logistic regression analysis, independent variables (BMI, menstrual status, and bone fractures) were found to be statistically insignificant (p > 0.05). Conclusions: Excessive sports activity can be hazardous in young female population. Lower BMI might be related to menstrual irregularity. Young female population should be informed about this relationship, especially athletes who are particularly at risk. Certain precautions should be taken into consideration in this population in order to get benefits of sports activity.
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    Reasons for clozapine discontinuation in patients with treatment-resistant schizophrenia
    (Elsevier Ireland Ltd, 2019) Ucok A.; Yağcıoğlu E.A.; Yıldız M.; Kaymak S.U.; Saka M.C.; Taşdelen R.; Danacı A.E.; Şenol Ş.H.
    Although clozapine is more effective than other antipsychotics in the treatment of schizophrenia, the rate of its discontinuation is also high. The aim of this retrospective chart-review study was to investigate the causes of clozapine discontinuation in patients with treatment-resistant schizophrenia. This study included a total of 396 patients with schizophrenia, 240 still on clozapine therapy and 156 who discontinued clozapine, and compared their clinical characteristics. Those who discontinued clozapine had a longer history of illness and more hospitalizations before clozapine and tended to be older. Inadequate response was more common among clozapine discontinuers compared to continuers. The most common reason for discontinuation was the side-effects associated with clozapine (49%). Discontinuation from patient decision or by the psychiatrist due to noncompliance was the second (29.7%) and discontinuation due to lack of efficacy was the third most frequent reason (21.3%). The patients who discontinued clozapine because of cardiac side effects were younger, had shorter duration of clozapine use, and had lower maximum clozapine dose compared to the other discontinuers. Our findings point out the importance of enhancing psychiatrists’ ability to handle manageable side effects to minimize discontinuations and maximize the benefits of clozapine in patients with treatment-resistant schizophrenia. © 2019 Elsevier B.V.