Browsing by Subject "ketoprofen"

Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA2LEN and AllerGen)
    (Blackwell Publishing Ltd, 2008) Bousquet J.; Khaltaev N.; Cruz A.A.; Denburg J.; Fokkens W.J.; Togias A.; Zuberbier T.; Baena-Cagnani C.E.; Canonica G.W.; Van Weel C.; Agache I.; Aït-Khaled N.; Bachert C.; Blaiss M.S.; Bonini S.; Boulet L.-P.; Bousquet P.-J.; Camargos P.; Carlsen K.-H.; Chen Y.; Custovic A.; Dahl R.; Demoly P.; Douagui H.; Durham S.R.; Van Wijk R.G.; Kalayci O.; Kaliner M.A.; Kim Y.-Y.; Kowalski M.L.; Kuna P.; Le L.T.T.; Lemiere C.; Li J.; Lockey R.F.; Mavale-Manuel S.; Meltzer E.O.; Mohammad Y.; Mullol J.; Naclerio R.; O'Hehir R.E.; Ohta K.; Ouedraogo S.; Palkonen S.; Papadopoulos N.; Passalacqua G.; Pawankar R.; Popov T.A.; Rabe K.F.; Rosado-Pinto J.; Scadding G.K.; Simons F.E.R.; Toskala E.; Valovirta E.; Van Cauwenberge P.; Wang D.-Y.; Wickman M.; Yawn B.P.; Yorgancioglu A.; Yusuf O.M.; Zar H.; Annesi-Maesano I.; Bateman E.D.; Kheder A.B.; Boakye D.A.; Bouchard J.; Burney P.; Busse W.W.; Chan-Yeung M.; Chavannes N.H.; Chuchalin A.; Dolen W.K.; Emuzyte R.; Grouse L.; Humbert M.; Jackson C.; Johnston S.L.; Keith P.K.; Kemp J.P.; Klossek J.-M.; Larenas-Linnemann D.; Lipworth B.; Malo J.-L.; Marshall G.D.; Naspitz C.; Nekam K.; Niggemann B.; Nizankowska-Mogilnicka E.; Okamoto Y.; Orru M.P.; Potter P.; Price D.; Stoloff S.W.; Vandenplas O.; Viegi G.; Williams D.
    [No abstract available]
  • No Thumbnail Available
    Item
    Ketoprofen gel improves low back pain in addition to IV dexketoprofen: a randomized placebo-controlled trial
    (W.B. Saunders, 2016) Serinken M.; Eken C.; Tunay K.; Golcuk Y.
    Objective Oligoanalgesia is common in emergency departments (EDs), and pain management is of concern for ED physicians. The aim of this study was to reveal the effect of ketoprofen gel in patients presenting with mechanical low back pain to the ED. Method All the study patients received intravenous dexketoprofen additional to study drugs. After dexketoprofen, 2 g of 2.5% ketoprofen gel or placebo was administered to the site with pain and tenderness. Pain relief at 15 and 30 minutes was measured by visual analog scale scores. Rescue drug need and adverse effects were also recorded. Results A total of 140 patients were enrolled into the study. The mean age of the study patients was 35 ± 12, and 56% (n = 79) of them were male. The mean pain reduction at 30 minutes was 52 ± 18 for ketoprofen gel and 37 ± 17 for placebo, and ketoprofen gel was better than placebo at 30 minutes (mean difference, 16 mm; 95% confidence interval, 10-21). Ten patients (14%) in the placebo group and 2 patients (3%) in the ketoprofen gel group needed rescue drug (P = .35). Conclusion Ketoprofen gel improves pain in patients presenting with mechanical low back pain to ED at 30 minutes in addition to intravenous dexketoprofen when compared to placebo. © 2016 Elsevier Inc.
  • No Thumbnail Available
    Item
    Topical ketoprofen versus placebo in children presenting with ankle sprain to the Emergency Department: A randomized controlled study
    (Lippincott Williams and Wilkins, 2020) Serinken M.; Eken C.; Tünay K.; Gölcük Y.
    Objective Despite the favorable data concerning topical agents use in outpatient clinics, they are not commonly in emergency departments (EDs). The present study aimed to compare the effect of 2.5% topical ketoprofen (gel form) to placebo in children presenting with ankle sprain to the ED. Study Design Children between 7 and 18 years old presenting with ankle sprain composed the study population. Study patients were randomized into 2 study arms: 2.5% ketoprofen gel and placebo administered in a 5-cm area locally. Pain improvements at 15 and 30 minutes were measured by visual analog scale. Results Median pain reductions at 15 minutes for ketoprofen and placebo groups were 27.5 (16-39) and 5 (4-10), respectively. Median changes in pain intensity at 30 minutes for ketoprofen and placebo gel groups were 48 (43-52) and 9 (6-16), respectively. When compared 2 arms for the pain improvement at 15 and 30 minutes, the differences between 2 study drugs were 20 (13-28) and 35 (29-41), respectively. There were 7 (12.7%) rescue drug needs in the placebo group and 1 (1.7%) in the ketoprofen group (difference, 10.9%; 95% confidence interval, -6% to 7%; P = 0.83). There were no adverse effects in either group. Conclusions Ketoprofen gel is superior to placebo in ceasing pain in children presenting with ankle sprain to the ED with a high safety profile. © Wolters Kluwer Health, Inc. All rights reserved.