Browsing by Subject "macular degeneration"

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    Tuberculosis anterior uveitis and choroidal tuberculosis granuloma
    (Gazi Eye Foundation, 2021) DOGRUYA S.; KAYIKCIOGLU O.R.
    In this study, we present a patient with pulmonary tuberculosis, who was diagnosed with uvetis and choroidal granuloma occuring as a new attack in the other eye. Visual acuity of a 26 year-old woman complaining about visual loss in the left eye and fuzziness in both eyes was 0.05 in the right eye and 0.5 in the left eye. Anterior segment examination was normal in the right eye and anterior chamber had 2+cells in the left eye. In the fundus examination of the right eye, diffuse chorioretinal atrophy and atrophy in macula were observed. In the examination of the left eye, macular nasal elevation and retinal pigment irregularity was detected. OCT showed atrophy of the fovea and subretinal fi brosis in the right eye , foveal nasal elevation and fi brosis in the left eye. In FFA, scar areas were observed in the right eye retina and there was, an active focus tbc granuloma and three scar areas in upper temporal of the left eye. The patient was followed-up under anti-Tbc treatment with the advice of pneumotologist and also topical cyclopegia and steroid treatment. The patient's visual acuity peaked in the left eye after a 12-month treatment. In the follow-ups, foci were observed in the posterior areas of the left eye. During the follow-up period, fresh foci were seen in adjacent areas of the posterior in the left eye in the second year. The patient is still under follow-up with anti-TBc treatment. Tuberculosis uveitis and choroidal granulomas are serious diseases which require long and careful follow-up. © 2021 Gazi Eye Foundation. All rights reserved.
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    A comparative study of type 1 neovascularization: Neovascular age-related macular degeneration versus pachychoroid neovasculopathy
    (SAGE Publications Ltd, 2022) Altinisik M.; Kurt E.; Sonmezer P.; Kayikcioglu O.; Ilker S.S.
    Purpose: This study aimed to compare type 1 choroidal neovascularization (CNV) characteristics in eyes with pachychoroid neovasculopathy (PNV) and neovascular age-related macular degeneration (nAMD) using optical coherence tomography angiography (OCTA). Methods: Treatment naive 23 eyes of 23 patients with PNV and 24 eyes of 24 patients with nAMD were evaluated. The height of pigment epithelial detachment (PED) and the central macular thickness were determined. OCTA sensitivity, CNV area, morphological patterns, and retinal superficial capillary plexus vessel density (SCP-VD) values were compared. The frequency of quiescent CNV, subretinal hyperreflective exudation (SHE), subretinal/intraretinal fluid, serous PED, double-layer sign (DLS), and pachyvessels were noted. Results: CNV was detected on OCTA in 83.3% of nAMD eyes and 91.3% of PNV eyes (p = 0.66). Indistinct pattern was more common (74% vs 50%) and the CNV area (mm2) was smaller in PNV (0.77 ± 0.54 vs 1.57 ± 1.43) but did not reach significant levels (p = 0.27 and 0.33 respectively). SCP-VD was similar between the groups (p = 0.38). Statistically significant differences were found between groups in age and subfoveal choroidal thickness (p < 0.05). DLS and pachyvessels were found to be more frequently in PNV (p < 0.05). However, both groups had similar rates of quiescent CNV, SHE, subretinal/intraretinal fluid, and serous PED (p > 0.05). Conclusion: Morphological features, area, and activation findings of type 1 CNV may play a limited role in differentiating nAMD and PNV cases. © The Author(s) 2021.