Browsing by Subject "medical device"

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    Hypopyon-like features: New dermoscopic criteria in the differential diagnosis of cutaneous lymphangioma circumscriptum and haemangiomas?
    (2012) Gencoglan G.; Inanir I.; Ermertcan A.T.
    Background Lymphangiomas are congenital malformations of the lymphatic system characterized by clusters of translucent vesicles. Dermoscopically, yellow and bluish lacunea according to the lymphatic or haematic content were described previously, but it is difficult to distinguish them from haemangioma. Observations In nine patients with cutaneous lymphangioma circumscriptum (CLC), hypopyon-like features were observed. None of the 10 patients with haemangioma had this finding. Conclusion Hypopyon-like features can be a useful dermoscopic pattern in differentiating CLC from haemangioma. © 2011 The Authors. Journal of the European Academy of Dermatology and Venereology © 2011 European Academy of Dermatology and Venereology.
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    Comparative analysis of XTT assay and xCELLigence system by measuring cytotoxicity of resveratrol in human cancer cell lines; [İnsan kanser hücre hatlarında resveratrol sitotoksisitesinin XTT testi ve xCELLigence sistemi ile karşılaştırmalı analizi]
    (Turkish Biochemistry Society, 2016) Atmaca H.; Bozkurt E.; Kısım A.; Uslu R.
    Objective: In vitro preliminary oncological and translational studies are mainly based on evaluating the cytotoxic effects of a specific compound on cultured cells. Resveratrol is a commercially available compound which is originally isolated from the roots of white hellebore and later from Polygonum cuspidatum. The objective of the study was to compare cytotoxicity data of Resveratrol from XTT end point assay with a real-time cell based xCELLigence system in terms of accuracy, sensitivity, speed and reproducibility in a panel of human cancer cell lines. Methods: XTT end point assay and real-time cell based xCELLigence system were used to evaluate cytotoxicity. Cytotoxicity results were verified by monitoring cells under phase-contrast microscope which were treated with IC50 values of resveratrol. Results: Resveratrol decreased cell viability in a timeand concentration-dependent manner in all cancer cell lines when tested by both the XTT assay and xCELLigence system. Standard deviations of the xCELLigence data were found to be lower than the data from XTT assay. Conclusion: The data from this study strongly imply that xCELLigence system has higher precision, more enlightening and more reproducible than XTT end point assay. © 2016 Turkish Biochemistry Society. All rights reserved.