Browsing by Subject "nephrology"

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    COVID-19 in pediatric nephrology centers in Turkey
    (Turkiye Klinikleri, 2022) Leventoğlu E.; Atikel Y.Ö.; Nalçacioğlu H.; Dursun I.; Dursun H.; Yildirim Z.Y.; Yildiz N.; Aksoy G.K.; Taşdemir M.; Çelakil M.; Kiliç B.D.; Selçuk Ş.Z.; Canpolat N.; Çakici E.K.; Özlü S.G.; Tülpar S.; Yüksel S.; Atmiş B.; Döven S.S.; Taner S.; Ertan P.; Kavaz A.; Bayram M.T.; Kalyoncu M.; Gülleroğlu K.; Kabasakal C.; Demir B.K.; Çiçek R.Y.; Bilge I.; Dönmez O.; Kara A.; Yavaşcan Ö.; Özçelik G.; Yildirim D.G.; Güler M.A.; Sönmez F.; Poyrazoğlu H.; Akman S.; Topaloğlu R.; Alpay H.; Bakkaloğlu S.A.
    Background/aim: There is limited data on COVID-19 disease in children with kidney disease. We aimed to investigate the characteristics and prognosis of COVID-19 in pediatric nephrology patients in Turkey. Materials and methods: This was a national, multicenter, retrospective cohort study based on an online survey evaluating the data between 11th March 2020 and 11th March 2021 as an initial step of a detailed pediatric nephrology COVID-19 registry. Results: Two hundred and three patients (89 girls and 114 boys) were diagnosed with COVID-19. One-third of these patients (36.9%) were between 10–15 years old. Half of the patients were on kidney replacement therapy: kidney transplant (KTx) recipients (n = 56, 27.5%), patients receiving chronic hemodialysis (n = 33, 16.3%) and those on peritoneal dialysis (PD) (n = 18, 8.9%). Fifty-four (26.6%) children were asymptomatic. Eighty-two (40.3%) patients were hospitalized and 23 (28%) needed intensive care unit admission. Fifty-five percent of the patients were not treated, while the remaining was given favipiravir (20.7%), steroid (16.3%), and hydroxychloroquine (11.3%). Acute kidney injury developed in 19.5% of hospitalized patients. Five (2.4%) had MIS-C. Eighty-three percent of the patients were discharged without any apparent sequelae, while 7 (3.4%) died. One hundred and eight health care staff were infected during the study period. Conclusion: COVID-19 was most commonly seen in patients who underwent KTx and received HD. The combined immunosuppressive therapy and frequent exposure to the hospital setting may increase these patients’ susceptibility. Staff infections before vaccination era were alarming, various precautions should be taken for infection control, particularly optimal vaccination coverage. © TÜBİTAK.
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    Comparison of infants and children with urolithiasis: a large case series
    (Springer Science and Business Media Deutschland GmbH, 2022) Baştuğ F.; Ağbaş A.; Tülpar S.; Yıldırım Z.N.Y.; Çiçek N.; Günay N.; Gemici A.; Çelik B.; Delebe E.Ö.Ç.; Nalçacıoğlu H.; Yılmaz A.; Gökçe İ.; Demircin G.; Hacıhamdioğlu D.Ö.; Yılmaz K.; Atmış B.; Yılmaz E.K.; Ertan P.; Dursun İ.; Aksu B.; Akbulut B.B.; Döven S.S.; Öner N.; Yel S.; Elmacı A.M.; Atikel Y.Ö.; Erfidan G.; Uysal B.; Bıyıklı N.; Yazıcıoğlu B.; Küçük N.; Çomak E.; Sever F.L.; Akil İ.; Aksoy Ö.; Alpay H.
    We evaluated the demographic features, etiologic risk factors, treatment strategies, and outcome of the infants and children with urolithiasis (UL). A retrospective multicenter study was conducted including 23 Pediatric Nephrology centers in Turkey. The medical records of 2513 children with UL were reviewed. One thousand, three hundred and four boys and 1209 girls (1.1:1) were reported. The mean age at diagnosis was 39.5 ± 35 months (0.4–231 months), and 1262 patients (50.2%) were in the first year of life (infants). Most of the cases with infantile UL were diagnosed incidentally. Microlithiasis (< 3 mm) was found in 794 patients (31.6%), and 64.5% of the patients with microlithiasis were infants. Stones were located in the pelvis-calyces in 63.2% (n: 1530) of the cases. The most common stone type was calcium oxalate (64.6%). Hypocitraturia was the most common metabolic risk factor (MRF) in children older than 12 months, but in infancy, hypercalciuria was more common. Fifty-five percent of the patients had received at least one medical treatment, mostly potassium citrate. At the end of a year’s follow-up, most of the patients with microlithiasis (85%) showed spontaneous remission. The rate of spontaneous stone resolution in infants was higher than in children. Spontaneous remission rate was higher in cases with MRF (− ) stones than in MRF (+) stones. However, remission rate with medical treatment was higher in cases with MRF (+) stones. This study represents the results of a large series of infants and children with UL and showed that there are several differences such as underlying metabolic and anatomic abnormalities, clinical course, and stone remission rates between infants and children with urinary stone disease. © 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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    The 6th of February earthquake and the Turkish Society of Pediatric Nephrology—organizational aspects of pediatric kidney care
    (Oxford University Press, 2023) Bakkaloglu S.A.; Yavaşcan Ö.; Yılmaz A.; Gülleroglu K.; Demir B.K.; Ertan P.; Poyrazoglu H.
    [No abstract available]
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    FRAILTY AND RELATED FACTORS IN ELDERLY PATIENTS WITH CHRONIC KIDNEY DISEASE
    (Turkish Geriatrics Society, 2023) Alp A.; Elbi H.; Toraman A.
    Introduction: Chronic kidney disease and frailty are two crucial clinical conditions increasing in prevalence globally. Both lead to severe complications that increase mortality and morbidity in patients. Conditions that may potentiate frailty in chronic kidney disease patients may complicate the follow-up of chronic disease and complicate long-term survival in this patient group. In this study, we aimed to evaluate frailty and related factors in chronic kidney disease patients over 65 years of age who were on dialysis and who were not. Materials and Methods: This cross-sectional study was carried out in geriatric chronic kidney disease patients followed in nephrology outpatient clinics or undergoing routine hemodialysis. Frailty was assessed using a scoring scale. Laboratory findings and their relationship with demographic and epidemiological data were investigated. Results: One hundred eighty-eight patients aged 65 and over were included in our study. Of the patients, 92 were female, and 96 were male. The mean age was 72.86 years. We found frailty in 82 patients (43.6%). Female gender, over 75 years old, under dialysis treatment, low-income status, and low education level were parameters significantly associated with frailty. In the regression analysis, we found that economic status and dialysis were variables that independently affected frailty in chronic kidney disease patients. Conclusions: In our study, the frequency of frailty was found to be high. Practical management and early assessment of frailty seem rational with the basic nephrological approach in patients with chronic kidney disease. Considering the high mortality rate among frail patients, we think these patients should be followed up more closely. © 2023, Turkish Geriatrics Society. All rights reserved.
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    Follow up of renal outcomes in children with solitary kidney
    (John Wiley and Sons Inc, 2023) Akyol Onder E.N.; Yilmaz O.; Taneli C.; Ertan P.
    Background: Solitary kidney (SK) affects 1/1000 people worldwide, and there are controversies concerning renal outcomes in these patients. This study aimed to investigate clinical findings and renal outcomes in children with SK and to compare the results for congenital (CSK) and acquired SK (ASK) groups. Methods: The study included patients that presented to our pediatric nephrology department with SK between January 2010 and January 2021. Demographic and clinical data were recorded retrospectively. Results: Of the 101 patients with SK, 71 had CSK (55 had unilateral renal agenesis and 16 had a multicystic dysplastic kidney) and 30 had ASK (17 had previously undergone unilateral nephrectomy due to a renal tumor and 13 had urological structural anomalies). There were nine patients (9%) with renal injury. The serum uric acid level was significantly higher and the estimated glomerular filtration rate was significantly lower in the patients with ASK compared with those with CSK (p = 0.005 and p < 0.001, respectively). There was a positive correlation between renal injury and the uric acid level (p < 0.001, r = 0.45). Conclusion: In addition to the management of blood pressure and proteinuria, it is important to control uric acid levels in patients with SK, especially those with ASK, to prevent renal injury. The ASK group has a greater risk of renal injury than the CSK group. There is a need for new markers to predict early stage renal damage in SK. © 2023 Japan Pediatric Society.