Browsing by Subject "parameters concerning the fetus, newborn and pregnancy"

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    The alteration in placental volume and placental mean grey value in growth-restricted pregnancies assessed by 3D ultrasound
    (Taylor and Francis Ltd., 2015) Artunc Ulkumen B.; Pala H.G.; Uyar Y.; Koyuncu F.M.; Bulbul Baytur Y.
    We aimed to evaluate the volumetric and echogenic alterations in placentas between the intrauterine growth restriction (IUGR) and normal pregnancies using three-dimensional ultrasound and virtual organ computer-aided analysis (VOCAL) software. This case-control prospective study consisted of 48 singleton pregnancies complicated by IUGR and 60 healthy singleton pregnancies matched for maternal age, gestational age and parity. Placental volume (PV) and placental volumetric mean grey values (MGV) were evaluated. PV (cm3) was analysed using the VOCAL imaging analysis program, and 3D histogram was used to calculate the volumetric MGV (%). PV was 278.50 ± 63.68 and 370.98 ± 97.82 cm3 in IUGR and control groups, respectively (p = 0.004). MGV of the placenta was 38.24 ± 8.41 and 38.24 ± 8.41 in IUGR and control groups, respectively (p = 0.30). receiver operator curve (ROC) curve analysis revealed that area under curve was 0.731 for PV. Correlation analysis revealed that PV was significantly associated with estimated fetal weight (r = 0.319, p = 0.003), biparietal diameter (r = 0.346, p = 0.002), head circumference (r = 0.269, p = 0.019), abdominal circumference (r = 0.344, p = 0.002) and femur length (r = 0.328, p = 0.004). PV was inversely related to the umbilical artery pulsatility index (r =-0.244, p = 0.017). To the best of our knowledge, this is the first study evaluating volumetric MGV in IUGR placentas by comparing them with healthy pregnancies. Our study showed that PV diminishes significantly in IUGR pregnancies, whereas volumetric MGV does not alter significantly. © 2015 © 2015 Taylor & Francis Group, LLC.
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    Pregnancy outcomes following the use of thiocolchicoside
    (Elsevier Inc., 2016) Ozturk Z.; Olmez E.; Gurpinar T.; Vural K.
    Thiocolchicoside is a commonly used muscle relaxant in orthopedic, rheumatologic or musculoskeletal disorders to treat painful muscle spasms. It is contraindicated in pregnancy and lactation. There is no previously published experience with thiocolchicoside exposure during pregnancy. In this observational study, we collected and evaluated 18 pregnancy outcomes of the women referred to our prenatal consultation service for thiocolchicoside exposure between 2007-2012, and offspring were followed up until 2 years of age. There were 16 live births, 1 spontaneous abortion and 1 elective termination of pregnancy. No major birth defect was observed. The mothers and their babies were free of perinatal complications. No growth or developmental abnormalities were found during follow-up period. Our findings add information on inadvertent use of thiocolchicoside in pregnancy. Further large prospective cohort studies are required to investigate this issue. © 2016 Elsevier Inc.
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    Anthropometric findings from birth to adulthood and their relation with karyotpye distribution in Turkish girls with Turner syndrome
    (Wiley-Liss Inc., 2016) Sari E.; Bereket A.; Yeşilkaya E.; Baş F.; Bundak R.; Aydin B.K.; Darcan S.; Dündar B.; Büyukinan M.; Kara C.; Adal E.; Akinci A.; Atabek M.E.; Demirel F.; Çelik N.; Özkan B.; Özhan B.; Orbak Z.; Ersoy B.; Doğan M.; Ataş A.; Turan S.; Gökşen D.; Tarim O.; Yüksel B.; Ercan O.; Hatun S.; Şimşek E.; Ökten A.; Abaci A.; Döneray H.; Özbek M.N.; Keskin M.; Önal H.; Akyürek N.; Bulan K.; Tepe D.; Emeksiz H.C.; Demir K.; Kizilay D.; Topaloğlu A.K.; Eren E.; Özen S.; Demirbilek H.; Abali S.; Akin L.; Eklioğlu B.S.; Kaba S.; Anik A.; Baş S.; Unuvar T.; Sağlam H.; Bolu S.; Özgen T.; Doğan D.; Çakir E.D.; Şen Y.; Andiran N.; Çizmecioğlu F.; Evliyaoğlu O.; Karagüzel G.; Pirgon O.; Çatli G.; Can H.D.; Gürbüz F.; Binay C.; Baş V.N.; Fidanci K.; Gül D.; Polat A.; Acikel C.; Cinaz P.; Darendeliler F.
    To evaluate the anthropometric features of girls with Turner syndrome (TS) at birth and presentation and the effect of karyotype on these parameters. Data were collected from 842 patients with TS from 35 different centers, who were followed-up between 1984 and 2014 and whose diagnosis age ranged from birth to 18 years. Of the 842 patients, 122 girls who received growth hormone, estrogen or oxandrolone were excluded, and 720 girls were included in the study. In this cohort, the frequency of small for gestational age (SGA) birth was 33%. The frequency of SGA birth was 4.2% (2/48) in preterm and 36% (174/483) in term neonates (P<0.001). The mean birth length was 1.3cm shorter and mean birth weight was 0.36kg lower than that of the normal population. The mean age at diagnosis was 10.1±4.4 years. Mean height, weight and body mass index standard deviation scores at presentation were -3.1±1.7, -1.4±1.5, and 0.4±1.7, respectively. Patients with isochromosome Xq were significantly heavier than those with other karyotype groups (P=0.007). Age at presentation was negatively correlated and mid-parental height was positively correlated with height at presentation. Mid-parental height and age at presentation were the only parameters that were associated with height of children with TS. The frequency of SGA birth was found higher in preterm than term neonates but the mechanism could not be clarified. We found no effect of karyotype on height of girls with TS, whereas weight was greater in 46,X,i(Xq) and 45,X/46,X,i(Xq) karyotype groups. © 2016 Wiley Periodicals, Inc.