Browsing by Subject "psychiatric diagnosis"

Now showing 1 - 11 of 11
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    Psychiatric disorders in patients attending a dermatology outpatient clinic
    (1998) Aktan Ş.; Özmen E.; Şanli B.
    Background: Psychiatric comorbidity in patients with skin disorders has been reported. Objective: To find out the prevalence of psychiatric disorders in dermatology outpatients and to investigate the factors that affect the psychiatric symptoms. Methods: 256 patients attending our dermatology outpatient clinic completed a 12-item General Health Questionnaire (GHQ) following their dermatologic examination. A standardized personal interview was performed to establish a psychiatric diagnosis in patients sampled by using a stratified random sampling method. Results: The prevalence of psychiatric disorders was found to be 33.4% in the study group. The mean of the total GHQ scores of the sample group (n = 256 patients) was 3.656. The duration of the dermatologic complaints, sex of the subjects, localization of the lesions, and dermatologic diagnosis did not affect the total GHQ scores of the patients. Conclusion: Psychiatric comorbidity in 33.4% of the dermatology outpatients indicates the need for considering emotional factors for an effective management of the cutaneous disorders.
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    Depression and anxiety in hypothyroidism
    (2003) Demet M.M.; Ozmen B.; Deveci A.; Boyvada S.; Adiguzel H.; Aydemir O.
    The aim of the study was to determine the prevalence and severity of depression and anxiety inpatients with hypothyroidism and to compare this with euthyroid patients. Thirty patients with hypothyroidism and 30 euthyroid controls attending the Endocrinology outpatient department of Celal Bayar University, Medical Faculty were included in the study. The hormonal screening was done by immunoassay and haemagglutination methods. Then, for psychiatric assessment, Hospital Anxiety and Depression Scale (HAD), Hamilton Depression Rating Scale (HAM-D), and Hamilton Anxiety Rating Scale (HAM-A) were used. There was no difference between the two groups in terms of demographic features. Total scores obtained from the scales used in the study did not differ significantly (p > 0.05). The frequency of items of both HAM-D and HAM-A did not show any differences in the two groups. By Wilks' Lambda discriminant analysis, depressive mood (HAM-D#1) was found to be the discriminating feature between the hypothyroid group and the euthyroid group. Therefore, depression and anxiety were not outstanding features in hypothyroidism. However, depression was more significant in the hypothyroid than euthyroid group.
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    The effect of chronic antidepressant treatment on serum brain-derived neurotrophic factor levels in depressed patients: A preliminary study
    (Elsevier Inc., 2005) Aydemir O.; Deveci A.; Taneli F.
    Recent studies suggested a role of brain-derived neurotrophic factor (BDNF) in depression. While BDNF levels are lower in depressed patients, antidepressant treatment increases serum BDNF levels of depressed patients. Our study aims to test the effect of chronic venlafaxine treatment on serum BDNF levels in patients with a major depressive disorder. Ten patients diagnosed as major depressive disorder according to DSM-IV are included in the study. Two of the patients had their first episode and were drug-naive, the other eight patients were drug-free for at least 4 weeks. The severity of depression was assessed with Hamilton Depression Rating Scale (HDRS). The control group consisted of ten age- and sex-matched subjects without any psychiatric disorder. Blood samples were collected at the baseline and after 12 weeks of antidepressant treatment (during remission). At the baseline the mean serum BDNF level was 17.9±9.1 ng/ml and the mean HDRS score was 23.2±4.6. Serum BDNF levels of the study group were significantly lower than in the control group (31.6±8.6 ng/ml). At the end of the study, the mean serum BDNF level was 34.6±7.1 ng/ml whereas the mean HDRS score was 8.2±3.9. From the baseline to the remission after 12 weeks of treatment, the increase in serum BDNF level and the decrease in HDRS score were statistically significant, respectively. When we compared the serum BDNF level of depressed patients at remission to that of the controls, there was no statistically significant difference. This study shows that venlafaxine treatment of depression improves serum BDNF level which may be considered as a nonspecific peripheral marker of depression. © 2004 Elsevier Inc. All rights reserved.
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    Residual symptoms in bipolar disorder: The effect of the last episode after remission
    (2007) Kaya E.; Aydemir Ö.; Selcuki D.
    In this study it is aimed to assess interepisode residual symptoms in remitted bipolar disorder patients with a hypothesis that the last episode recovered has implications on residual symptomatology. The study was carried out with 23 bipolar patients diagnosed as mania (BP-M) and 20 bipolar patients diagnosed as depression (BP-D) in their last episode, and with 22 healthy controls in a university hospital clinic. All patients were in remission for at least 6 months. In the assessment Hamilton Depression Rating Scale (HAM-D), Young Mania Rating Scale (YMRS), Stroop Test, Auditory Verbal Learning Test (AVLT), increased latency positive-evoked potentials (P300), Global Assessment of Functioning Scale (GAF), and Social Functioning Scale (SFS) were used cross-sectionally. In affective symptomatology, the BP-M group had higher YMRS scores, and the BP-D group had higher HAM-D scores compared to the controls. P300 test results revealed low amplitude in the BP-D group. In the AVLT, verbal learning and delayed recall were significantly lower in the two bipolar groups. The Stroop tasks were not different in the groups. Concerning the SFS, social withdrawal was impaired in the two bipolar groups, whereas dependency-competency was impaired in the BP-M and employment/occupation was impaired in the BP-D group. As a conclusion, bipolar patients recovering from depressive episode may experience more impairment in daily functioning due to residual depressive symptoms and impairment of attention and memory. © 2007 Elsevier Inc. All rights reserved.
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    Serum brain-derived neurotrophic factor level in dysthymia: A comparative study with major depressive disorder
    (Elsevier Inc., 2007) Aydemir Ö.; Deveci A.; Taskin O.E.; Taneli F.; Esen-Danaci A.
    In this present work, it is aimed to demonstrate BDNF serum concentrations in patients with dysthymia and to compare them with BDNF serum concentrations in patients with major depressive disorder and healthy subjects. The study was carried out in Celal Bayar University Hospital, Manisa, Turkey. Seventeen patients with dysthymia, 24 patients with major depressive disorder and 26 subjects without any psychiatric diagnosis and any psychiatric treatment were included in the study. The severity of depression was assessed with 17-item HAM-D. All subjects were asked to give their written consent. Blood samples were collected at baseline. Serum BDNF was kept at - 70 °C before testing, and assayed with an ELISA Kit (Promega; Madison, WI, USA), after dilution with the Block and Sample solution provided with the kit. The data were subjected to the analysis of variance. The BDNF serum concentrations of the dysthymia group (mean = 28.9 ± 9.2 ng/ml) were significantly higher than that of the major depressive disorder group (21.2 ± 11.3 ng/ml) (p = 0.002), and it was not different from the level of the control group (31.4 ± 8.8 ng/ml). BDNF serum concentrations and HAM-D score did not have any significant correlation in the dysthymia and major depression groups (r = - 0.276, p = 0.086). The low level of BDNF in patients with dysthymic disorder seems to point out that BDNF changes in mood disorders are state-dependent and vary according to the severity of depressive episodes. © 2007 Elsevier Inc. All rights reserved.
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    Serum BDNF levels in suicide attempters related to psychosocial stressors: A comparative study with depression
    (2008) Deveci A.; Aydemir O.; Taskin O.; Taneli F.; Esen-Danaci A.
    Although many studies have examined the neurobiological aspects of suicide, the molecular mechanisms and pathophysiologic mechanisms associated with suicide remain unclear. In this study, it is aimed to investigate whether there is a difference in serum brain-derived neurotrophic factor (BDNF) levels among suicide attempters without a major psychiatric disorder, compared to major depressive disorder patients and healthy subjects. It was undertaken with the hypothesis that suicide per se lowers serum BDNF levels, since it is a source of stress. The study was carried out in Celal Bayar University Hospital, Manisa, Turkey. Ten suicide attempters, 24 patients with major depressive disorder and 26 subjects without any psychiatric diagnosis and any psychiatric treatment were included in the study. All subjects were asked to give their written consent. Blood samples were collected at the baseline. Serum BDNF was kept at -70°C before testing, and assayed with an ELISA kit (Promega; Madison, Wisc., USA) after dilution with the block and sample solution provided with the kit. The data were subjected to the Kruskal-Wallis test for nonparametric analysis of variance. Mean serum BDNF levels were significantly lower in the suicide group (21.2 ± 12.4 ng/ml) and the major depressive disorder group (21.2 ± 11.3 ng/ml) than the control group (31.4 ± 8.8 ng/ml; p = 0.004). These results suggest that BDNF may play an important role in the neurobiology of suicidal behavior. BDNF levels may be a biological marker for suicidal behavior. To investigate the role of BDNF in suicide, further studies with a wider sample size and a variety of psychiatric diagnoses accompanying suicide attempt are needed. Copyright © 2007 S. Karger AG.
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    Serum brain-derived neurotrophic factor levels in pain syndromes: A comparative study with major depression
    (Cukurova Univ Tip Fakultesi Psikiyatri Anabilim Dali, 2008) Taşkin E.O.; Aydemir Ö.; Deveci A.; Taneli F.; Selçuki D.; Cerrahoǧlu L.; Danaci A.E.
    Objective: In this study, it is aimed to compare the level of Brain-Derived Neurotrophic Factor (BDNF) of patients with migraine and fibromyalgia to that of depressive patients and healthy subjects in order to answer the question whether stress is related to pain syndromes. Methods: In the migraine group 27 patients and in the fibromyalgia group 19 patients without any previous antidepressant treatment and psychiatric diagnosis were included. In the depression group, 24 patients with at least eight weeks of antidepressant-free period were invited to the study. In the depression group no co-morbid diagnosis in the first axis was made. Twenty-six subjects without any previous psychiatric diagnosis and psychiatric treatment consisted the control group. For making diagnosis of depression and other first axis disorders Structured Clinical Interview for DSM- IV (SCID-I) was used in all study groups. For the assessment of the severity of depression Hamilton Depression Rating Scale (HAM-D) was applied. The diagnosis of migraine was made according to the criteria of International Headache Society. For the diagnosis of the fibromyalgia the criteria of American College of Rheumatology was used. The severity of pain was assessed with visual analogue scale (VAS) in the migraine and fibromyalgia groups. Serum BDNF was kept at -70°C before testing, and assayed with an ELISA Kit (Promega; Madison, WI, USA), after dilution with the Block and Sample solution provided with the kit. The data were subjected to Kruskal Wallis Test in the comparison of serum BDNF levels. Results: The serum BDNF level of the depression group (21.2±11.3 ng/ml) was statistically lower (p<0.0001) than the level of the migraine group (32.2±10.1 ng/ml), fibromyalgia group (30.7±8.9 ng/ml) and the control group (31.4±8.8 ng/ml). The level of BDNF was not significantly different in the migraine, fibromyalgia and control groups. There was no significant correlation between serum BDNF levels, and age and gender. In pain syndromes there was no signification correlation between serum BDNF levels, and mean scores of HAM-D and VAS (r= 0.085; p= 0.579 and r= 0.191; p= 0.204 respectively). Similarly there was no significant correlation between serum BDNF levels and HAM-D scores in the depression group (r=0.122; p= 0.579). Conclusions: Even though the pain syndromes were suggested to be associated with stress, in this present work, serum BDNF level as one of the markers of stress does not support this hypothesis. This might be related to the factor that in pain syndromes such as fibromyalgia or migraine, serum BDNF level may be affected by the alteration in peripheral platelet functions. Furthermore in a limited chronic stress serum BDNF levels tend to be not affected and this may play a significant role in our results.
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    The eating attitudes, sleep and personality characteristics, and effects of on acne severity in adolescents with acne vulgaris
    (2021) Bilaç Ö.; Bilaç C.; Tahıllıoğlu A.; Uzun A.D.; Dilcan M.; Önder A.; Kavurma C.; Uzunoğlu G.
    Background: Acne vulgaris (AV) is a very common dermatological problem during adolescence. It is reported that it has a multifactorial etiology and nutritional attitudes, insufficient and poor-quality sleep may cause increased severity of AV. Aim: We aimed to investigate the sleep, eating attitudes and personality traits, and their effects on acne severity in adolescents with acne. Methods: The study sample was formed of 37 adolescent girls aged 12–18 years who presented at the University Dermatology Clinic and were diagnosed with AV and 37 adolescents without AV-matched age and gender. Eating attitude test, Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) Personality Inventory Child Form, and child and parent forms of DSM-5 Level 2 Sleep Disorders were applied to in both groups. The AV severity assessed by using the Global Acne Grading Scale (GAGS). Psychiatric diagnosis was excluded with clinical interview according to the Schedule for Affective Disorders and Schizophrenia for school-aged children: Present and Lifetime Version (K-SADS-PL-DSM-5-T). Results: The mean age of adolescents with and without AV was 15.3 (standard deviation [SD] = 1.7), 15.4 (SD = 1.8), respectively. The mean disease duration of adolescents with AV was 20.4 (SD = 15.2) months, and the mean GAGS score was 23.24 (SD = 9.4). It was determined that eating attitudes, sleep, and personality characteristics of adolescents were similar in both groups. Eating attitudes, sleep, and personality characteristics had no direct effect on acne severity. Conclusion: Although this study demonstrates that eating attitudes, sleep, and personality characteristics were similar in adolescents with and without AV and these variables had no effect on acne severity, these results may have been obtained because of the severity scores of adolescents with AV were “moderate.” There is a need for researches examining these variables in adolescents with “severe” AV. © 2021 Turkish Journal of Dermatology.
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    Who predict ADHD with better diagnostic accuracy?: Parents or teachers?
    (Taylor and Francis Ltd., 2021) Tahıllıoğlu A.; Bilaç Ö.; Uysal T.; Ercan E.S.
    Objective: The objectives of the study were to determine which parents or teachers predict attention-deficit/hyperactivity disorder (ADHD) better in children and adolescents, and to detect both diagnostical and symptomatological agreement levels across informant reports. Method: A total of 417 cases aged 6–14 from a non-referred community sample were assessed by a semi-structured interview, parent- and teacher-rated ADHD Rating Scale-IV. Also, impairment criteria were taken into account to ensure the gold standard diagnosis for ADHD. The measures of sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy were calculated in each categorical sample. Besides, the agreement between parent and teacher reports of ADHD was investigated. Results: Parents and teachers had similar diagnostic accuracy for predicting ADHD. Both parents and teachers predicted ADHD in similar accuracy in both boys and girls, separately. However, girls were found to be more predictable by both parents and teachers compared to boys. Parents with lower education levels had worse diagnostic accuracy than both parents with higher education levels and teachers. Low to moderate agreement and correlations between parent and teacher ADHD reports were detected. Conclusion: In general, parents and teachers seem to predict ADHD in similar accuracy. Nevertheless, child gender and parental education level may alter the predictability power for ADHD. The findings can guide for clinicians that how to evaluate observation reports of parents and teachers to make accurate ADHD diagnosis in patients. © 2021 The Nordic Psychiatric Association.
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    Evaluation of Quality of Life and Psychiatric Comorbidity in Adolescents with Social Media Addiction; [Ergenlerde Sosyal Medya Bağımlılığında Yaşam Kalitesi ve Psikiyatrik Komorbiditenin Değerlendirilmesi]
    (Istanbul Universitesi, 2021) Hamidi F.; Tahıllıoğlu A.; Bilaç Ö.; Önder A.
    Objective: The time spent on social media and smartphones by children and adolescents has increased in recent times. The problematic use of social media can be the cause or result of many problems such as depression, anxiety disorder, academic failure, and social phobia. Despite its close relationship with psy-chopathologies, the problematic use of social media is often not evaluated during a psychiatric interview. In this study, we aimed to evaluate the quality of life and psychiatric comorbidities in adolescents with social media addiction. Methods: This study included 30 adolescents who received a score of 5 or higher from the Social Media Addiction Scale for Adolescents-Short Form. The Quality of Life Scale for Children was applied to adolescents and their parents in both the groups. In the analysis of the data, number, percentage, mean, standard deviation, Mann–Whitney U test, and Spearman’s correlation test were used in the Statistical Package for the Social Sciences version 20.0 program. Results: The mean ages of the adolescents with social media addiction and control group were 13.5 ± 1.8 and 13.4 ± 1.73 years, respectively. When the adolescents with and without social media addiction were compared in terms of quality of life, physical health, psychosocial, and total scores, there were significant differences according to both parental and self-reports (P < .05). Psychiatric diagnoses were also found higher in adolescents with social media addiction (P < .001). Conclusion: Our research can be a guide for identifying the risks and problems that may arise from problematic social media use and for the preventive and treatment medicine studies in this field. © Istanbul Universitesi. All rights reserved.
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    The Prevalence, Sociodemographic, and Comorbidity Characteristics of Turkish Children with Cognitive Disengagement Syndrome
    (Istanbul Universitesi, 2024) Tahıllıoğlu A.; Bilaç Ö.; Kardaş B.; Kardaş Ö.; Bolat G.Ü.; Duman N.S.; Gökten E.S.; Uytun M.Ç.; Kahraman Ö.; Demirci E.; Taşdemir A.I.; Şan Z.L.; Şen F.D.; Yılmaz E.K.; Türkel G.Y.; Demirtaş M.E.; Çakır B.; Ercan E.S.
    Objective: Cognitive disengagement syndrome, formerly known as sluggish cognitive tempo, is defined as mental fogginess, daydreaming, and sluggishness. This study aimed to determine the prevalence and sociodemographic characteristics of children with cognitive disengagement syndrome and to examine the relationship between cognitive disengagement syndrome and psychiatric disorders. Methods: About 268 randomly chosen Turkish primary school children aged 7-11 years from 4 different cities were included in this study. Both teachers and parents completed the cognitive disengagement syndrome scanning scale of the Child Behavior Checklist and the Barkley Child Attention Survey. Psychiatric diagnoses in children were assessed using a semi-structured clinical interview. Four separate cognitive disengagement syndrome measurements were performed, matching informants with scales. Results: The prevalence of cognitive disengagement syndrome was estimated with a range of 4.9%-10.9%, depending on the way of measurement. Logistic regression analyses revealed that paternal psychopathology (odds ratio = 6.7) and low maternal education (odds ratio = 3.1) increased while advanced maternal age (odds ratio = 0.7) decreased the risk of cognitive disengagement syndrome. Although cognitive disengagement syndrome was found to be more prevalent in children with chronic diseases, this association no longer remained in the full logistic regression model. Attention-defic it/hyperactivity disorder was the most observed disorder and accompanied 42.9%-75% of the cases with higher cognitive disengagement syndrome. However, there was no strong support in favor of associations between cognitive disengagement syndrome and depression and anxiety as a whole. Conclusion: This study provides the first estimates regarding the prevalence and the sociodemographic characteristics of Turkish children with cognitive disengagement syndrome. Cognitive disengagement syndrome seems to be relatively more prevalent in Turkey than in Western cultures. Children whose fathers had a psychiatric disorder, whose mothers had low education, and who were at younger ages should be scrutinized for cognitive disengagement syndrome. © Author(s)-Available online at neuropsychiatricinvestigation.org.