Browsing by Subject "salicylic acid"
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Item Arthroscopic removal of the osteoid osteoma on the neck of the talus(2004) Yercan H.S.; Okcu G.; Ozalp T.; Osiç U.Juxta-articular osteoid osteomas arising around the ankle are unusual. Tumors arising on the neck of the talus will commonly produce symptoms mimicking monoarticular arthritis or trauma. Patients are usually treated for arthritis or ankle sprain, which often leads to a delay in definitive diagnosis. We present an arthroscopic removal of an osteoid osteoma on the neck of talus, and review the literature. © Springer-Verlag 2003.Item Improvement in symptoms of psoriasis in a child after treatment with grass pollen specific allergen immunotherapy(Dermatologia Pediatrica, 2007) Sogut A.; Yilmaz O.; Yuksel H.Psoriasis is a chronic inflammatory disease of skin in which Th1 lymphocytes have a central role. Similar to all inflammatory diseases, additional inflammation may lead to the exacerbation of manifestations. Allergic asthma is the chronic eosinophilic inflammatory disease of the bronchial mucosa in which Th2 lymphocyte activity predominates. A nine year old boy who had been under conventional topical treatment for psoriasis without improvement for three months, presented to the outpatient department with recurrent cough, dyspnea and wheezing of one year duration. The physical examination revealed white plaques on extensor surfaces of elbows and knees as well as prolonged expirium and wheezing. Positive allergen skin prick test against "olea europea" and "fraxinus excelsior" pollens were observed. Inhaled steroids and allergen specific immunotherapy were initiated with the diagnosis of allergic asthma. Psoriatic findings regressed without requirement for an additional topical treatment during follow up along with asthma findings. As a conclusion, inflammatory stress of allergic asthma may aggravate psoriasis and treatment with allergen specific immunotherapy may help decrease findings of psoriasis.Item Open, prospective, multi-center, two-part study of patient preference with monthly ibandronate therapy in women with postmenopausal osteoporosis switched from daily or weekly alendronate or risendronate-BONCURE: Results of Turkish sub-study(Galenos Yayincilik,, 2012) Eskiyurt N.; Irdesel J.; Sepici V.; Uǧurlu H.; Kirazli Y.; Ardiç F.; Bütün B.; Akyüz G.; Cerrahoǧlu L.; Şendur Ö.F.; Yalçin P.; Öncel S.; Saridoǧan M.; Sarpel T.; Tosun M.; Kutsal Y.G.; Şenel K.; Gürsoy S.; Cantürk F.; Demir H.; Özdener F.; Öncel H.Aim: BONCURE (Bonviva for Current Bisphosphonate Users Regional European Trial), aimed to evaluate patient preference with monthly ibandronate in women with postmenopausal osteoporosis who previously received daily or weekly alendronate or risendronate. Materials and Methods: This prospective, open-label study consisted of two sequential stages, Part A (screening) and Part B (treatment). Patients enrolled into Part A completed the Candidate Identification Questionnaire (CIQ). In Part B, after completing the Osteoporosis Patient Satisfaction Questionnaire (OPSAT-Q), patients received monthly oral ibandronate 150 mg for 6 months. Following treatment, patients completed the OPSAT-Q and Preference Questionnaire. Results: A total of 223 patients (mean age, 63.7±9.51 years) were enrolled in Part A from Turkey. Among them, 103 (46.2%) answered "YES" to at leastone CIQ question. The mean composite OPSAT-Q domain scores increased for convenience (mean change, 15.3±17.7 points), quality of life (10.4±20.4points), overall satisfaction (11.9±22.7 points), and side effects (3.3±18.8 points). At month 6, 177 subjects (92.7%) preferred once-monthly dosing scheduleand 99.0% were compliant (≥80%) with study treatment. Thirty (15.6%) subjects experienced mild to moderate adverse events, mostly gastrointestinal. Conclusion: Postmenopausal women with osteoporosis prefer and are more satisfied and compliant with monthly dosing of ibandronate than daily or weekly bisphosphonate treatment.Item Nonmelanoma Skin Cancer of the Head and Neck: Prevention(2012) Oghan F.; Eskiizmir G.; Unlu H.; Cingi C.The importance and effectiveness of prevention efforts and strategies for skin cancers are reviewed. Topical sunscreens and their proper use are presented. Topical and ingested forms of natural, synthetic, or biologic chemical agents that are potentially efficacious for chemoprevention are listtdldted and discussed. © 2012 Elsevier Inc.Item Cold pressed Pinus halepensis Mill. seed oil for potential health applications: Analgesic, anti-inflammatory effects, and assessment of inflammatory mediators by RT-qPCR in skin wound healing(Elsevier Ireland Ltd, 2024) Ait Atmane S.; Batır M.B.; Özbek Z.A.; Ergönül P.G.; Balcan E.; Ait Eldjoudi D.; Özkale E.; Bribi N.; Khettal B.Ethnopharmacological relevance: Pinus halepensis Mill. seed (Pinaceae), commonly known as “Zgougou,” is widely consumed in the Mediterranean region and has long been used to treat diseases including bronchitis, rheumatism, infection, and inflammation. Aim of the study: The present study was focused on the investigation of some pharmacological activities, such as analgesic, anti-inflammatory, and wound healing effects, of cold-pressed oil of Pinus halepensis Mill. seed (COPHS). Materials and methods: The fixed oil of Pinus halepensis seed was extracted by a cold pressing process. The analgesic activity of COPHS was examined by acetic acid and formalin-induced contortion and pain tests. The anti-inflammatory effects were evaluated in carrageenan and formalin induced paw and ear edema models. Wound healing potential was assessed on an experimental skin wound, and the expression levels of inflammation mediators were determined by RT-qPCR in skin wound healing. Results: The results showed analgesic efficacy through significant inhibition of abdominal cramps (59.15%) and pain (75.91%). In addition, this oil exerted an anti-inflammatory effect by inhibiting ear (62.25%) and paw (70.00%) edema. The COPHS stimulated wound contraction in experimental skin wound healing with a contraction rate of 89.23% with notable reduction of TNF-α and NF-kB expression levels in the treated groups. Conclusions: This study provided for the first time the pharmacological profile, particularly the analgesic, anti-inflammatory, and healing effects, of fixed oil extracted by cold pressing from the seed of Pinus halepensis Mill. © 2023 Elsevier B.V.