A case of mycetoma successfully treated with itraconazole and co-trimoxazole

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dc.contributor.authorGündüz K.
dc.contributor.authorÖrgüç Ş.
dc.contributor.authorDemireli P.
dc.contributor.authorInanir I.
dc.contributor.authorSürücüoglu S.
dc.contributor.authorOvali G.Y.
dc.date.accessioned2024-07-22T08:23:21Z
dc.date.available2024-07-22T08:23:21Z
dc.date.issued2006
dc.description.abstractA 29-year-old woman with swelling, multiple nodules and discharging sinuses of her right foot is presented. A single nodule on the sole was excised 15 years ago and since then she has had recurrent attacks of swelling and discharging sinuses that improved partially with antibiotics. Magnetic resonance images (MRI) revealed an ill-defined mass predominantly with low signal intensity on T2W images. Within the granulomata, multiple unenhancing foci, with low T1W and T2W signal most likely representing the fungal balls or grains were detected. Histopathological examination revealed large clusters of microorganisms resembling fungal hyphae and bacteria, which were surrounded by mixed inflammatory infiltrate cells and stained positively by PAS and Gomori's methenamine silver stain. As minimal regression was seen on MRI with 4 months' itraconazole (200 mg day-1) treatment, co-trimoxazole (160 TMP/800 SMX b.i.d.) was added to treatment. Complete remission was established by MRI examination after 10 months with this combination therapy. © 2006 The Authors.
dc.identifier.DOI-ID10.1111/j.1439-0507.2006.01260.x
dc.identifier.issn14390507
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19489
dc.language.isoEnglish
dc.subjectAdult
dc.subjectAnti-Infective Agents
dc.subjectAntifungal Agents
dc.subjectFemale
dc.subjectFoot Dermatoses
dc.subjectFungi
dc.subjectHumans
dc.subjectHyphae
dc.subjectItraconazole
dc.subjectMaduromycosis
dc.subjectMagnetic Resonance Imaging
dc.subjectMicroscopy
dc.subjectMycetoma
dc.subjectTrimethoprim-Sulfamethoxazole Combination
dc.subjectBacteria (microorganisms)
dc.subjectamikacin
dc.subjectciprofloxacin
dc.subjectcotrimoxazole
dc.subjectdapsone
dc.subjectitraconazole
dc.subjectketoconazole
dc.subjectadult
dc.subjectantibiotic therapy
dc.subjectarticle
dc.subjectcase report
dc.subjectcell infiltration
dc.subjectcombination chemotherapy
dc.subjectfemale
dc.subjectfoot sole
dc.subjectfungus hyphae
dc.subjecthistopathology
dc.subjecthuman
dc.subjectimage analysis
dc.subjectinflammation
dc.subjectmycetoma
dc.subjectnuclear magnetic resonance imaging
dc.subjectpriority journal
dc.subjectremission
dc.subjectskin nodule
dc.subjectstaining
dc.subjectswelling
dc.titleA case of mycetoma successfully treated with itraconazole and co-trimoxazole
dc.typeArticle

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