Molecular epidemiology of hepatitis B virus; [Hepatit B virusunun moleküler epidemiyolojisi]

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dc.contributor.authorArıkan A.
dc.contributor.authorŞanlıdağ T.
dc.date.accessioned2024-07-22T08:11:43Z
dc.date.available2024-07-22T08:11:43Z
dc.date.issued2016
dc.description.abstractIn addition to high viral copy number during replication, HBV reverse transciptase also does not have a proofreading function, therefore, many HBV genotypes, subgenotypes, mutants and recombinants can emerge. To date, 10 HBV genotypes (A-J) and almost 40 subgenotypes have been identified. Genotype A is dominant in Northwest Europe, North America and Africa; genotype B and C are common in Asian countries; genotype C is more dominant in East and Southeast Asian countries. Genotype D is widespread in the whole world and is endemic in the Meditteranean area, the Middle East and Western Asia. Genotype E is dominant in Western Africa and genotype H has been found in Central and South America. Genotype G has been reported in France, Germany and America. The genotype H is found in Central America. Recently identified genotype I, a recombination of genotypes A, C and G, was isolated in Vietnam and Laos. The most recent genotype J was identified in the Ryukyu islands in Japan and this genotype has a relationship between gibon/ orangutan genotypes and human genotype C. In this review, HBV genotypes and subgenotypes, their geographic distributions and clinical aspects were overviewed. © 2016 AVES Ibrahim Kara. All rights reserved.
dc.identifier.DOI-ID10.5152/kd.2016.14
dc.identifier.issn1301143X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/15760
dc.language.isoTurkish
dc.publisherAVES Ibrahim Kara
dc.subjectAfrica
dc.subjectCentral America
dc.subjectclinical feature
dc.subjectFrance
dc.subjectgenotype
dc.subjectgeographic distribution
dc.subjectGermany
dc.subjectHepatitis B virus
dc.subjecthuman
dc.subjectJapan
dc.subjectMiddle East
dc.subjectmolecular epidemiology
dc.subjectnonhuman
dc.subjectNorth America
dc.subjectorangutan
dc.subjectSouth America
dc.subjectViet Nam
dc.titleMolecular epidemiology of hepatitis B virus; [Hepatit B virusunun moleküler epidemiyolojisi]
dc.typeReview

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