Acute pancreatitis in Turkey: Results of a nationwide multicenter study

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dc.contributor.authorKoksal, AS
dc.contributor.authorTozlu, M
dc.contributor.authorSezgin, O
dc.contributor.authorOguz, D
dc.contributor.authorKalkan, IH
dc.contributor.authorAltntas, E
dc.contributor.authorYaras, S
dc.contributor.authorBilgic, Y
dc.contributor.authorYildirim, AE
dc.contributor.authorBarutcu, S
dc.contributor.authorHakim, GD
dc.contributor.authorSoytuerk, M
dc.contributor.authorBengi, G
dc.contributor.authorOzseker, B
dc.contributor.authorYurci, A
dc.contributor.authorKoc, DO
dc.contributor.authorIrak, K
dc.contributor.authorKasap, E
dc.contributor.authorCindoruk, M
dc.contributor.authorOruc, N
dc.contributor.authorÜnal, NG
dc.contributor.authorSen, I
dc.contributor.authorGokden, Y
dc.contributor.authorSaruc, M
dc.contributor.authorÜnal, H
dc.contributor.authorEminler, AT
dc.contributor.authorToka, B
dc.contributor.authorBasir, H
dc.contributor.authorSaglam, O
dc.contributor.authorErguel, B
dc.contributor.authorGuel, O
dc.contributor.authorBueyuektorun, I
dc.contributor.authorOzel, M
dc.contributor.authorSair, U
dc.contributor.authorKosem, G
dc.contributor.authorNedirli, F
dc.contributor.authorTahtaci, M
dc.contributor.authorParlak, E
dc.date.accessioned2025-04-10T10:37:32Z
dc.date.available2025-04-10T10:37:32Z
dc.description.abstractBackground: Acute pancreatitis (AP) is the most common gastrointestinal disease requiring hospitalization, with significant mortality and morbidity. We aimed to evaluate the clinical characteristics of AP and physicians ' compliance with international guidelines during its management. Methods: All patients with AP who were hospitalized at 17 tertiary centers in Turkey between April and October 2022 were evaluated in a prospective cohort study. Patients with insufficient data, COVID-19 and those aged below 18 years were excluded. The definitions were based on the 2012 revised Atlanta criteria. Results: The study included 2144 patients (median age:58, 52 % female). The most common etiologies were biliary (n = 1438, 67.1 %), idiopathic (n = 259, 12 %), hypertriglyceridemia (n = 128, 6 %) and alcohol (n = 90, 4.2 %). Disease severity was mild in 1567 (73.1 %), moderate in 521 (24.3 %), and severe in 58 (2.6 %) patients. Morphology was necrotizing in 4.7 % of the patients. The overall mortality rate was 1.6 %. PASS and BISAP had the highest accuracy in predicting severe pancreatitis on admission (AUC:0.85 and 0.81, respectively). CT was performed in 61 % of the patients, with the majority (90 %) being within 72 h after admission. Prophylactic NSAIDs were not administered in 44 % of the patients with post-ERCP pancreatitis (n = 86). Antibiotics were administered to 53.7 % of the patients, and 38 % of those received them prophylactically. Conclusions: This prospective study provides an extensive report on clinical characteristics, management and outcomes of AP in real -world practice. Mortality remains high in severe cases and physicians ' adherence to guidelines during management of the disease needs improvement in some aspects. (c) 2023 IAP and EPC. Published by Elsevier B.V. All rights reserved.
dc.identifier.e-issn1424-3911
dc.identifier.issn1424-3903
dc.identifier.urihttp://hdl.handle.net/20.500.14701/43068
dc.language.isoEnglish
dc.titleAcute pancreatitis in Turkey: Results of a nationwide multicenter study
dc.typeArticle

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