The effect of diazepam premedication and penthothal induction on upper airway changes by ultrasonography; [Ḋiyazepam premeḋ ikasyonu ve ṫ iyopental ̇ indü kṡiyonunun ÿst hava yolu deǧ̇ iş̇ ikl̇ ikleṙ ine etk̇iṡiṅin ultrasonograḟ ik deǧ erlenḋ iṙ ilmeṡi]

Ok G.; Tekin Mirzai I.; Tarhan S.; Lüleci N.

The effect of diazepam premedication and penthothal induction on upper airway changes by ultrasonography; [Ḋiyazepam premeḋ ikasyonu ve ṫ iyopental ̇ indü kṡiyonunun ÿst hava yolu deǧ̇ iş̇ ikl̇ ikleṙ ine etk̇iṡiṅin ultrasonograḟ ik deǧ erlenḋ iṙ ilmeṡi]

Date

2004

Authors

Abstract

We aimed to determine diazepam premedication effect on airway changes during anesthesia induction with thiopental. 40 patients (ASA I-II, aged 20-50 years) who were planned to undergo elective operations were divided into 2 groups. 10 mg diazepam orally one hour before operation, was given to Group I premedication was not given to Group II. We monitored pulse, TA, ECG, SPO2, PETCO2 and kept head in neutral position. We recorded ultrasonographic views of tongue movements by ultrasound probe located below the chin while the patients were ventilating by mask. For anesthesia induction Na pentothal was given iv until lash reflex diminished. Tongue movements were monitored before induction until one minute after lash reflex and consciousness were lost. Difficulty in mask ventilation was recorded. The distance between ultrasound probe and back-front points of tongue arc was measured and differences were recorded. The demografic data and ASA classification of groups were similar (p>0.05). A particular movement of tongue in any direction was not observed in either group (p>0.05). Difficult ventilation with mask was observed in 30% of all patients. In patients with premedication apnea rate was found to be high. We concluded that difficult ventilation with face mask was not result of tongue movement. Difficult ventilation with mask is not related with premedication or anesthetics given for induction alone; diazepam premedication is thought to potantialize central apnea effect of thiopenthal used for induction.