Two-dimensional molybdenum disulfide/polymer-coated bioactive glass scaffolds for tissue engineering: Fabrication, structural, mechanical, bioactivity, and radiation interaction properties

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dc.contributor.authorDeliormanli A.M.
dc.contributor.authorEnsoylu M.
dc.contributor.authorALMisned G.
dc.contributor.authorTekin H.O.
dc.date.accessioned2024-07-22T08:02:32Z
dc.date.available2024-07-22T08:02:32Z
dc.date.issued2023
dc.description.abstractMolybdenum disulfide (MoS2)-based nanostructures are widely used in environmental protection and biomedicine owing to their biological, physical, chemical, electrical, and mechanical properties. In this study, polycaprolactone (PCL)- and polylactide-co-glycolide (PLGA)-coated bioactive glass scaffolds containing MoS2 nanoparticles are prepared, and their usability in bone tissue engineering applications is evaluated. Borate bioactive glass scaffolds are fabricated using the replication method and coated with PCL or PLGA solutions (5 wt%) containing MoS2 (0.1, 0.2, 0.5, 1, and 2 wt%) nanoparticles. The structural and mechanical properties of the scaffolds and their bioactivity in simulated body fluids are investigated comprehensively. The ionization–radiation-shielding properties are investigated using Monte Carlo simulations. The results show that the polymer coating layer and presence of MoS2 nanoparticles in the polymer matrix improves the mechanical properties of the scaffolds. The addition of MoS2 nanoparticles to the structure increases the hydroxyapatite-forming ability of bioactive glass-based composites. Additionally, the prepared composite scaffolds exhibit high radiation-shielding ability owing to the presence of MoS2 nanoparticles embedded in the polymer matrix that shields the glass surface. Bioactive glass composite scaffolds containing MoS2 nanoparticles demonstrate promising potential for bone regeneration and radiation-shielding applications. © 2023 Elsevier Ltd and Techna Group S.r.l.
dc.identifier.DOI-ID10.1016/j.ceramint.2023.04.110
dc.identifier.issn02728842
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11887
dc.language.isoEnglish
dc.publisherElsevier Ltd
dc.subjectBioactive glass
dc.subjectBiomechanics
dc.subjectBody fluids
dc.subjectBone
dc.subjectFabrication
dc.subjectIntelligent systems
dc.subjectLayered semiconductors
dc.subjectMolybdenum disulfide
dc.subjectMonte Carlo methods
dc.subjectNanoparticles
dc.subjectPlastic coatings
dc.subjectPolymer matrix composites
dc.subjectRadiation shielding
dc.subjectScaffolds (biology)
dc.subjectTissue regeneration
dc.subjectBone regeneration
dc.subjectComposite scaffolds
dc.subjectEngineering fabrication
dc.subjectGlass scaffolds
dc.subjectMechanical interactions
dc.subjectPolymer matrices
dc.subjectScaffolds for tissue engineering
dc.subjectStructural interactions
dc.subjectTissues engineerings
dc.subjectTwo-dimensional
dc.subjectHydroxyapatite
dc.titleTwo-dimensional molybdenum disulfide/polymer-coated bioactive glass scaffolds for tissue engineering: Fabrication, structural, mechanical, bioactivity, and radiation interaction properties
dc.typeArticle

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