Evaluation of neurodegeneration through visual evoked potentials in restless legs syndrome

Simple item page
dc.contributor.authorKısabay A.
dc.contributor.authorSarı U.S.
dc.contributor.authorKorkmaz T.
dc.contributor.authorDinçhorasan G.
dc.contributor.authorYılmaz H.
dc.contributor.authorSelçuki D.
dc.date.accessioned2024-07-22T08:11:22Z
dc.date.available2024-07-22T08:11:22Z
dc.date.issued2016
dc.description.abstractRestless legs syndrome (RLS) is a disease characterized by some type of dysesthesia, an indescribable abnormal sensation in the extremities. Our objective was to determine whether the visual evoked potentials (VEP) can be used as a quantitative monitoring method to evaluate demyelination-remyelination and neurodegeneration in the patients with RLS. The present study was carried out prospectively. It was planned to determine normal or pathological conditions in the form of increased latency or decreased amplitude of VEP and to evaluate possible pathologies in the visual and retinal pathways at early stages and at months 3 and 6 of follow-up in the patients with RLS (with or without iron deficiency anemia), in those without RLS (at the time of diagnosis prior to any medical therapy) without any visual symptoms. It was observed that latency of VEP improved but didn’t return to normal limits following treatment with dopamin agonists, iron, or combination of both and that there was no significant difference between the post-treatment data and those of the control group. These results in combination with the fact that the latencies and amplitudes didn’t return to normal levels despite the 6-month-treatment but showed a progressive course with partial regeneration suggests that there was incomplete remyelination. It should be kept in mind that this syndrome is likely to be a part of neurodegenerative process. © 2016, Belgian Neurological Society.
dc.identifier.DOI-ID10.1007/s13760-016-0631-4
dc.identifier.issn03009009
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/15632
dc.language.isoEnglish
dc.publisherSpringer-Verlag Italia s.r.l.
dc.subjectAdult
dc.subjectAnemia, Iron-Deficiency
dc.subjectDopamine Agonists
dc.subjectEvoked Potentials, Visual
dc.subjectFemale
dc.subjectHumans
dc.subjectIron
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectNerve Degeneration
dc.subjectRestless Legs Syndrome
dc.subjectcyanocobalamin
dc.subjectferritin
dc.subjectfolic acid
dc.subjecthemoglobin
dc.subjectdopamine receptor stimulating agent
dc.subjectiron
dc.subjectadult
dc.subjectArticle
dc.subjectcontrolled study
dc.subjectdemyelination
dc.subjectdysesthesia
dc.subjectelectrocorticography
dc.subjectfollow up
dc.subjecthematocrit
dc.subjecthuman
dc.subjectiron binding capacity
dc.subjectiron deficiency anemia
dc.subjectmajor clinical study
dc.subjectmiddle aged
dc.subjectnerve degeneration
dc.subjectprospective study
dc.subjectremyelinization
dc.subjectrestless legs syndrome
dc.subjectvisual evoked potential
dc.subjectAnemia, Iron-Deficiency
dc.subjectcomplication
dc.subjectfemale
dc.subjectmale
dc.subjectpathophysiology
dc.subjectrestless legs syndrome
dc.titleEvaluation of neurodegeneration through visual evoked potentials in restless legs syndrome
dc.typeArticle

Files

Collections

Scopus Koleksiyonu