In vitro assessment of degradation and mineralisation of V2O5substituted borate bioactive glass scaffolds

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dc.contributor.authorDeliormanli A.M.
dc.date.accessioned2024-07-22T08:14:54Z
dc.date.available2024-07-22T08:14:54Z
dc.date.issued2014
dc.description.abstractBioactive glasses are promising scaffold materials for bone regeneration because of their unique ability to convert to hydroxyapatite (HA) in vivo, and their ability to bond with bone and soft tissues. In this study, borate based (13-93B3) bioactive glass powders containing up to 3 wt- %V2O5were prepared by the melt quench technique. Vanadium was chosen because of its therapeutic action. It is known to promote initial wound healing and this may be especially beneficial to applications involving diabetic patients and soft tissue healing. Bioactive glass scaffolds were fabricated using the polymer foam replication method. In vitro degradation and bioactivity of the scaffolds were evaluated in simulated body fluid under static conditions. Results revealed that the vanadium-containing borate glasses have higher degradation rates compared to the bare borate glass 13-93B3. Due to low chemical durability, substituted glasses exhibited a good in vitro bioactive response. Taking into account the high in vitro HA forming ability, borate glass scaffolds containing V+5therapeutic ions are promising candidates for bone tissue engineering applications. © 2014 W. S. Maney & Son Ltd.
dc.identifier.DOI-ID10.1179/1753555714Y.0000000167
dc.identifier.issn10667857
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/16670
dc.language.isoEnglish
dc.publisherManey Publishing
dc.subjectBioactive glass
dc.subjectBiodegradation
dc.subjectBody fluids
dc.subjectBorate minerals
dc.subjectDegradation
dc.subjectHydroxyapatite
dc.subjectScaffolds
dc.subjectTissue
dc.subjectTissue regeneration
dc.subjectVanadium
dc.subjectVanadium compounds
dc.subjectBone regeneration
dc.subjectBone tissue engineering
dc.subjectChemical durability
dc.subjectReplication method
dc.subjectScaffold materials
dc.subjectSimulated body fluids
dc.subjectSoft tissue healing
dc.subjectStatic conditions
dc.subjectScaffolds (biology)
dc.titleIn vitro assessment of degradation and mineralisation of V2O5substituted borate bioactive glass scaffolds
dc.typeArticle

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