Impairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Control: A MASK-air Real-World Study

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dc.contributor.authorSousa-Pinto B.
dc.contributor.authorLouis G.
dc.contributor.authorRodrigues J.
dc.contributor.authorGiuliano A.F.M.
dc.contributor.authorBaiardini I.
dc.contributor.authorBraido F.
dc.contributor.authorCzarlewski W.
dc.contributor.authorBedbrook A.
dc.contributor.authorHaahtela T.
dc.contributor.authorValiulis A.
dc.contributor.authorBrussino L.
dc.contributor.authorCecchi L.
dc.contributor.authorCruz A.A.
dc.contributor.authorGemicioglu B.
dc.contributor.authorFokkens W.J.
dc.contributor.authorIvancevich J.C.
dc.contributor.authorKlimek L.
dc.contributor.authorKraxner H.
dc.contributor.authorKuna P.
dc.contributor.authorKupczyk M.
dc.contributor.authorKvedariene V.
dc.contributor.authorLarenas-Linnemann D.
dc.contributor.authorLouis R.
dc.contributor.authorNadif R.
dc.contributor.authorNiedoszytko M.
dc.contributor.authorOkamoto Y.
dc.contributor.authorOllert M.
dc.contributor.authorPapadopoulos N.G.
dc.contributor.authorPatella V.
dc.contributor.authorPawankar R.
dc.contributor.authorPham-Thi N.
dc.contributor.authorPfaar O.
dc.contributor.authorRegateiro F.S.
dc.contributor.authorRoche N.
dc.contributor.authorRouadi P.W.
dc.contributor.authorSamolinski B.
dc.contributor.authorSastre J.
dc.contributor.authorSavouré M.
dc.contributor.authorScichilone N.
dc.contributor.authorSheikh A.
dc.contributor.authorTaborda-Barata L.
dc.contributor.authorToppila-Salmi S.
dc.contributor.authorYorgancioglu A.
dc.contributor.authorZidarn M.
dc.contributor.authorAnto J.M.
dc.contributor.authorZuberbier T.
dc.contributor.authorCanonica G.W.
dc.contributor.authorVentura M.T.
dc.contributor.authorFonseca J.A.
dc.contributor.authorPétré B.
dc.contributor.authorBousquet J.
dc.date.accessioned2024-07-22T08:02:13Z
dc.date.available2024-07-22T08:02:13Z
dc.date.issued2023
dc.description.abstractBackground: EQ-5D-5L (EuroQOL, 5 Domains, 5 Levels) is a widely used health-related quality-of-life instrument, comprising 5 domains. However, it is not known how each domain is impacted by rhinitis or asthma control. Objective: To assess the association between rhinitis or asthma control and the different EQ-5D-5L domains using data from the MASK-air mHealth app. Methods: In this cross-sectional study, we assessed data from all MASK-air users (2015-2021; 24 countries). For the levels of each EQ-5D-5L domain, we assessed rhinitis and asthma visual analog scales (VASs) and the combined symptom-medication score (CSMS). We built ordinal multivariable models assessing the adjusted association between VAS/CSMS values and the levels of each EQ-5D-5L domain. Finally, we compared EQ-5D-5L data from users with rhinitis and self-reported asthma with data from users with rhinitis alone. Results: We assessed 5354 days from 3092 users. We observed an association between worse control of rhinitis or asthma (higher VASs and CSMS) and worse EQ-5D-5L levels. In multivariable models, all VASs and the CSMS were associated with higher levels of pain/discomfort and daily activities. For anxiety/depression, the association was mostly observed for rhinitis-related tools (VAS nose, VAS global, and CSMS), although the presence of self-reported asthma was also associated with worse anxiety/depression. Worse mobility (“walking around”) was particularly associated with VAS asthma and with the presence of asthma. Conclusions: A worse rhinitis control and a worse asthma control are associated with higher EQ-5D-5L levels, particularly regarding pain/discomfort and activity impairment. Worse rhinitis control is associated with worse anxiety/depression, and poor asthma control with worse mobility. © 2023 American Academy of Allergy, Asthma & Immunology
dc.identifier.DOI-ID10.1016/j.jaip.2023.08.006
dc.identifier.issn22132198
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11770
dc.language.isoEnglish
dc.publisherAmerican Academy of Allergy, Asthma and Immunology
dc.rightsAll Open Access; Green Open Access
dc.subjectAsthma
dc.subjectCross-Sectional Studies
dc.subjectHealth Status
dc.subjectHumans
dc.subjectPain
dc.subjectQuality of Life
dc.subjectRhinitis, Allergic
dc.subjectSurveys and Questionnaires
dc.subjectadolescent
dc.subjectadult
dc.subjectaged
dc.subjectallergic rhinitis
dc.subjectanxiety disorder
dc.subjectArticle
dc.subjectasthma
dc.subjectcombined symptom medication score
dc.subjectcontrolled study
dc.subjectcross-sectional study
dc.subjectdaily life activity
dc.subjectdata analysis
dc.subjectdepression
dc.subjectdisease association
dc.subjectEuropean Quality of Life 5 Dimensions 5 Level questionnaire
dc.subjectfemale
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectpain
dc.subjectpractice guideline
dc.subjectquality of life
dc.subjectquestionnaire
dc.subjectrespiratory tract disease assessment
dc.subjectself care
dc.subjectself report
dc.subjectvery elderly
dc.subjectvisual analog scale
dc.subjectwalking
dc.subjectwalking difficulty
dc.subjectallergic rhinitis
dc.subjectasthma
dc.subjecthealth status
dc.subjectpain
dc.titleImpairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Control: A MASK-air Real-World Study
dc.typeArticle

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