Rational antibiotic use

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dc.contributor.authorTunger O.
dc.contributor.authorKarakaya Y.
dc.contributor.authorCetin C.B.
dc.contributor.authorDinc G.
dc.contributor.authorBorand H.
dc.date.accessioned2024-07-22T08:22:02Z
dc.date.available2024-07-22T08:22:02Z
dc.date.issued2009
dc.description.abstractBackground: Development of resistance to antimicrobial agents and increase of cost as the result of unnecessary and inappropriate use of antibiotics has become a global health problem. Therefore many strategies, which are aimed at optimizing antibiotic therapy, have been developed until now. In Turkey, an antibiotic restriction policy as a governmental solution was applied to decrease the antibiotic use and especially costs by Ministry of Health in 2003. The aim of this study is to evaluate the rational antibiotic use and the impact of the implementation of new restriction policy, with their reinforcement by infectious disease specialist, on the hospital wide use of antibiotics. Methodology: The data of the inpatients received antibiotics (n=495) during January-June 2006 were compared with our previous study performed by the same methodology before the restriction policy in 1998. In both studies, prospective active daily surveillance of patients was performed by three infectious disease specialists. The appropriateness of antibiotic therapy was determined using the criteria described by Kunin and Jones. The data were analyzed by using SPSS for Windows. Results: While the rate of antibiotic use decreased from 16.6% to 11.3%, rational use increased after the restriction policy (p<0.001). Besides the specific antibiotic use increasing, prophylactic antibiotic use was found decreased (p<0.001). Mostly determined irrationality was the prophylactic uses in both studies. As expected, infectious disease specialist examinations resulted in an increase in the appropriate antibiotic use. Conclusions: The restriction policy was effective in decreasing the antibiotic consumption and increasing the rational antibiotic prescription in our hospital. Copyright © 2008 Tunger et al.
dc.identifier.DOI-ID10.3855/jidc.54
dc.identifier.issn20366590
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18872
dc.language.isoEnglish
dc.publisherJournal of Infection in Developing Countries
dc.rightsAll Open Access; Gold Open Access; Green Open Access
dc.subjectaciclovir
dc.subjectamikacin
dc.subjectamphotericin B
dc.subjectamphotericin B lipid complex
dc.subjectantibiotic agent
dc.subjectcarbapenem derivative
dc.subjectcephalosporin derivative
dc.subjectfluconazole
dc.subjectisepamicin
dc.subjectnetilmicin
dc.subjectpiperacillin plus tazobactam
dc.subjectpolypeptide antibiotic agent
dc.subjectquinoline derived antiinfective agent
dc.subjecttimentin
dc.subjectadult
dc.subjectantibiotic resistance
dc.subjectbacterial infection
dc.subjectclinical practice
dc.subjectcontrolled study
dc.subjectdrug utilization
dc.subjectfemale
dc.subjectfinancial management
dc.subjectgovernment
dc.subjecthealth care policy
dc.subjecthospital patient
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmedical record review
dc.subjectmedical specialist
dc.subjectprescription
dc.subjectprophylaxis
dc.subjectreview
dc.subjectTurkey (republic)
dc.subjectuniversity hospital
dc.subjectunnecessary procedure
dc.titleRational antibiotic use
dc.typeReview

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