Relationship of insulin resistance in chronic haemodialysis patients with inflammatory indicators, malnutrition, echocardiographic parameters and 24 hour ambulatory blood pressure monitoring

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dc.contributor.authorKurat S.
dc.contributor.authorColak H.B.
dc.contributor.authorToraman A.
dc.contributor.authorTekçe H.
dc.contributor.authorUlman C.
dc.contributor.authorBayturan O.
dc.date.accessioned2024-07-22T08:20:51Z
dc.date.available2024-07-22T08:20:51Z
dc.date.issued2010
dc.description.abstractObjective. The relationship between malnutrition, echocardiographic parameters, 24 h ambulatory blood pressure (ABP) parameters and decreased insulin sensitivity index (ISI-S) in chronic haemodialysis patients was investigated. Material and methods. ISI-S and inflammatory indicators were measured. The nutritional state was assessed by malnutrition score. Echocardiography and 24 h ABP were performed 1 day before the second haemodialysis session of the week. Results. ISI-S was inversely correlated with the night-time mean blood pressure (BP)/day-time mean BP ratio (p 0.021) and malnutrition score (p < 0.01). High-sensitivity C-reactive protein, night-time mean BP/day-time mean BP and vena cava collapse index were independent risk factors affecting ISI-S (p < 0.001; β 0.412, p 0.025; β 0.204, p < 0.001; β 0.465). Conclusions. The decrease in ISI-S along with the hypervolaemia suggests that volume overload is a contributory factor in the pathogenesis of insulin resistance in patients with chronic renal failure. This study indicates that, in addition to the traditional cardiovascular risk factors in these patients, insulin resistance can be regarded as a risk factor, but not an independent one, mainly a reflection of the underlying culprit, hypervolaemia. © 2010 Informa Healthcare.
dc.identifier.DOI-ID10.3109/00365591003733682
dc.identifier.issn16512065
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18358
dc.language.isoEnglish
dc.subjectAged
dc.subjectBlood Pressure
dc.subjectBlood Pressure Monitoring, Ambulatory
dc.subjectCircadian Rhythm
dc.subjectCross-Sectional Studies
dc.subjectEchocardiography
dc.subjectFemale
dc.subjectHumans
dc.subjectInflammation
dc.subjectInsulin Resistance
dc.subjectKidney Diseases
dc.subjectMale
dc.subjectMalnutrition
dc.subjectMiddle Aged
dc.subjectRenal Dialysis
dc.subjectRisk Factors
dc.subjectSensitivity and Specificity
dc.subjectVena Cava, Inferior
dc.subjectadiponectin
dc.subjectC reactive protein
dc.subjectinterleukin 6
dc.subjectleptin
dc.subjecttumor necrosis factor alpha
dc.subjectadult
dc.subjectaged
dc.subjectarticle
dc.subjectblood pressure monitoring
dc.subjectcardiovascular risk
dc.subjectchronic kidney failure
dc.subjectclinical article
dc.subjectechocardiography
dc.subjectfemale
dc.subjecthemodialysis
dc.subjecthuman
dc.subjecthypertension
dc.subjecthypervolemia
dc.subjectinflammation
dc.subjectinsulin resistance
dc.subjectmale
dc.subjectmalnutrition
dc.subjectpriority journal
dc.subjectrisk assessment
dc.subjectrisk factor
dc.titleRelationship of insulin resistance in chronic haemodialysis patients with inflammatory indicators, malnutrition, echocardiographic parameters and 24 hour ambulatory blood pressure monitoring
dc.typeArticle

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