Asthma phenotypes in Turkey: a multicenter cross-sectional study in adult asthmatics; PHENOTURK study

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dc.contributor.authorYildiz F.
dc.contributor.authorMungan D.
dc.contributor.authorGemicioglu B.
dc.contributor.authorYorgancioglu A.
dc.contributor.authorDursun B.
dc.contributor.authorOner Erkekol F.
dc.contributor.authorOgus C.
dc.contributor.authorTurktas H.
dc.contributor.authorBogatekin G.
dc.contributor.authorTopcu F.
dc.contributor.authorDeveci F.
dc.contributor.authorBayram H.
dc.contributor.authorTor M.
dc.contributor.authorKalyoncu A.F.
dc.date.accessioned2024-07-22T08:10:50Z
dc.date.available2024-07-22T08:10:50Z
dc.date.issued2017
dc.description.abstractBackground and Aims: To evaluate asthma phenotypes in patients with asthma from different regions of Turkey. Methods: A total of 1400 adult asthmatic patients (mean (SD) age: 44.0 (13.9) years, 75% females) from 14 centers across Turkey were included in this study and a standard questionnaire was applied between the time period of February 2011–January 2012. Results: The disease onset ≥ 40 years of age was higher percentage in obese vs. normal/overweight patients and nonallergic vs. allergic patients (P < 0.01). The percentage of patients who had FEV1 values over 80% was higher in allergic than nonallergic and normal/overweight than obese patients (P < 0.01). Uncontrolled asthmatics have more severe disease (P < 0.01). There were more frequent hospital admissions in nonallergic and uncontrolled asthmatics (P < 0.01). Chronic rhino-sinusitis was the leading comorbid disorder in normal/overweight and allergic asthma, while gastroesophageal reflux disorder was more frequent in nonallergic and uncontrolled asthma (P < 0.01). Asthma control rate was the highest (39.0%) in patients from Marmara region among all geographical regions (P < 0.05). Conclusion: In conclusion, our findings revealed existence of clinical/trigger related phenotypes based on BMI, allergic status, control level and geographical region with more frequent respiratory dysfunction and/or adverse health outcomes in uncontrolled, obese and nonallergic phenotypes. © 2015 John Wiley & Sons Ltd
dc.identifier.DOI-ID10.1111/crj.12326
dc.identifier.issn17526981
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/15400
dc.language.isoEnglish
dc.publisherBlackwell Publishing Ltd
dc.subjectAdult
dc.subjectAsthma
dc.subjectComorbidity
dc.subjectCross-Sectional Studies
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectObesity
dc.subjectPhenotype
dc.subjectRisk Factors
dc.subjectSurveys and Questionnaires
dc.subjectTurkey
dc.subjectadolescent
dc.subjectadult
dc.subjectaged
dc.subjectallergy
dc.subjectArticle
dc.subjectasthma
dc.subjectbody mass
dc.subjectchronic rhinosinusitis
dc.subjectcomorbidity
dc.subjectcontrolled study
dc.subjectcross-sectional study
dc.subjectdisease control
dc.subjectdisease severity
dc.subjectfemale
dc.subjectforced expiratory volume
dc.subjectgastroesophageal reflux
dc.subjectgeographic distribution
dc.subjecthospital admission
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectobesity
dc.subjectonset age
dc.subjectphenotype
dc.subjectsex difference
dc.subjectTurkey (republic)
dc.subjectasthma
dc.subjectclinical trial
dc.subjectcomplication
dc.subjectmiddle aged
dc.subjectmulticenter study
dc.subjectphenotype
dc.subjectquestionnaire
dc.subjectrisk factor
dc.subjectTurkey
dc.titleAsthma phenotypes in Turkey: a multicenter cross-sectional study in adult asthmatics; PHENOTURK study
dc.typeArticle

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