Questions in Mild Asthma: An Official American Thoracic Society Research Statement

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dc.contributor.authorMohan A.
dc.contributor.authorLugogo N.L.
dc.contributor.authorHanania N.A.
dc.contributor.authorReddel H.K.
dc.contributor.authorAkuthota P.
dc.contributor.authorO'Byrne P.M.
dc.contributor.authorGuilbert T.
dc.contributor.authorPapi A.
dc.contributor.authorPrice D.
dc.contributor.authorJenkins C.R.
dc.contributor.authorKraft M.
dc.contributor.authorBacharier L.B.
dc.contributor.authorBoulet L.-P.
dc.contributor.authorYawn B.P.
dc.contributor.authorPleasants R.
dc.contributor.authorLazarus S.C.
dc.contributor.authorBeasley R.
dc.contributor.authorGauvreau G.
dc.contributor.authorIsrael E.
dc.contributor.authorSchneider-Futschik E.K.
dc.contributor.authorYorgancioglu A.
dc.contributor.authorMartinez F.
dc.contributor.authorMoore W.
dc.contributor.authorSumino K.
dc.date.accessioned2024-07-22T08:02:33Z
dc.date.available2024-07-22T08:02:33Z
dc.date.issued2023
dc.description.abstractBackground: Patients with mild asthma are believed to represent the majority of patients with asthma. Disease-associated risks such as exacerbations, lung function decline, and death have been understudied in this patient population. There have been no prior efforts from major societies to describe research needs in mild asthma. Methods: A multidisciplinary, diverse group of 24 international experts reviewed the literature, identified knowledge gaps, and provided research recommendations relating to mild asthma definition, pathophysiology, and management across all age groups. Research needs were also investigated from a patient perspective, generated in conjunction with patients with asthma, caregivers, and stakeholders. Of note, this project is not a systematic review of the evidence and is not a clinical practice guideline. Results: There are multiple unmet needs in research on mild asthma driven by large knowledge gaps in all areas. Specifically, there is an immediate need for a robust mild asthma definition and an improved understanding of its pathophysiology and management strategies across all age groups. Future research must factor in patient perspectives. Conclusions: Despite significant advances in severe asthma, there remain innumerable research areas requiring urgent attention in mild asthma. An important first step is to determine a better definition that will accurately reflect the heterogeneity and risks noted in this group. This research statement highlights the topics of research that are of the highest priority. Furthermore, it firmly advocates the need for engagement with patient groups and for more support for research in this field. Copyright © 2023 by the American Thoracic Society.
dc.identifier.DOI-ID10.1164/rccm.202304-0642ST
dc.identifier.issn1073449X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11896
dc.language.isoEnglish
dc.publisherAmerican Thoracic Society
dc.rightsAll Open Access; Green Open Access
dc.subjectAsthma
dc.subjectCaregivers
dc.subjectHumans
dc.subjectSocieties, Medical
dc.subjectUnited States
dc.subjectbeta adrenergic receptor stimulating agent
dc.subjectbronchodilating agent
dc.subjectcorticosteroid
dc.subjectlong acting muscarinic receptor blocking agent
dc.subjectmuscarinic receptor blocking agent
dc.subjectshort acting beta 2 agonist
dc.subjectunclassified drug
dc.subjectArticle
dc.subjectasthma
dc.subjectdisease exacerbation
dc.subjecthuman
dc.subjectmedical research
dc.subjectmultidisciplinary team
dc.subjectpathophysiology
dc.subjectasthma
dc.subjectcaregiver
dc.subjectmedical society
dc.subjectUnited States
dc.titleQuestions in Mild Asthma: An Official American Thoracic Society Research Statement
dc.typeArticle

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