Retrospective evaluation of patients diagnosed solid pseudopapillary neoplasms of the pancreas

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dc.contributor.authorErcelep O.
dc.contributor.authorOzdemir N.
dc.contributor.authorTuran N.
dc.contributor.authorTopcu T.O.
dc.contributor.authorUysal M.
dc.contributor.authorTanriverdi O.
dc.contributor.authorDemirci U.
dc.contributor.authorTaskoylu B.Y.
dc.contributor.authorUrakcı Z.
dc.contributor.authorDuran A.O.
dc.contributor.authorAksoy A.
dc.contributor.authorMenekse S.
dc.contributor.authorOzcelik M.
dc.contributor.authorGumus M.
dc.date.accessioned2024-07-22T08:09:05Z
dc.date.available2024-07-22T08:09:05Z
dc.date.issued2019
dc.description.abstractPurpose: Solid pseudopapillary neoplasm (SPN) is a rare, low-grade neoplasm with excellent prognosis. In this study, we evaluated clinicopathological characteristics of patients diagnosed with SPN retrospectively. Methods: This is a retrospective study intended to characterize patients with the diagnosis of SPN between 2005 and 2015. Clinicopathological features, recurrence rate, and overall survival of 28 patients were recorded. Malignant SPN criteria were defined as the presence of distant metastasis (developed at diagnosis or during follow up) or lymph node involvement. Results: The mean age at diagnosis was 42 (range: 17-41). Among patients, 82% (n = 23) were female and 17.9% (n = 5) were male. The mean size of tumor was 5.81 cm (range: 2-15). The mean follow up period was 55.6 months, 1-year survival was 96.5% and 5-year survival rate was 88%. A total of 25 patients were alive at the end of follow-up period and 3 of the patients became exitus due to disease. Two patients had a metastatic presentation in livers at the diagnosis and metastasis developed in 3 patients during follow-up (liver of 1 patient, peritoneum in 1 patient and liver and peritoneum in 1 patient). The reason of admission was headache in 68% patients. The type of operation was frequently subtotal pancreatectomy (n = 11, 39.3%) and distal pancreatectomy (n = 10, 35.7%). Tumors were located frequently in body and tail regions (n = 18, 64.3%) and the number of patients with malignant criteria was 6 (21.4%). Although the mean age of malignant patients was significantly higher than benign patients (P = 0.046), there was no significant difference between 2 groups in terms of gender, tumor size, capsule invasion, perineural invasion, vascular invasion, and margin status. Conclusion: SPN is a rarely seen tumor with low malignity potential. Surgical resection provides long-term survival rate even in local invasion or metastasis conditions. © 2018 Elsevier Inc.
dc.identifier.DOI-ID10.1016/j.currproblcancer.2018.06.014
dc.identifier.issn01470272
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/14664
dc.language.isoEnglish
dc.publisherMosby Inc.
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAged
dc.subjectCarcinoma, Papillary
dc.subjectFemale
dc.subjectFollow-Up Studies
dc.subjectHumans
dc.subjectLymphatic Metastasis
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectNeoplasm Invasiveness
dc.subjectPancreatectomy
dc.subjectPancreatic Neoplasms
dc.subjectPrognosis
dc.subjectRetrospective Studies
dc.subjectSurvival Rate
dc.subjectYoung Adult
dc.subjectantineoplastic agent
dc.subjectabdominal distension
dc.subjectabdominal pain
dc.subjectadjuvant chemotherapy
dc.subjectadolescent
dc.subjectadult
dc.subjectArticle
dc.subjectbackache
dc.subjectcancer diagnosis
dc.subjectcancer radiotherapy
dc.subjectcancer recurrence
dc.subjectcancer survival
dc.subjectclinical article
dc.subjectclinical feature
dc.subjectdistal pancreatectomy
dc.subjectdistant metastasis
dc.subjectfemale
dc.subjectfollow up
dc.subjectheadache
dc.subjecthuman
dc.subjectjaundice
dc.subjectliver metastasis
dc.subjectlymph node metastasis
dc.subjectmale
dc.subjectoverall survival
dc.subjectpancreatectomy
dc.subjectperineural invasion
dc.subjectperitoneum metastasis
dc.subjectpruritus
dc.subjectrecurrent disease
dc.subjectretrospective study
dc.subjectsolid pseudopapillary tumor
dc.subjecttumor invasion
dc.subjecttumor volume
dc.subjectyoung adult
dc.subjectaged
dc.subjectmiddle aged
dc.subjectmortality
dc.subjectpancreas tumor
dc.subjectpapillary carcinoma
dc.subjectpathology
dc.subjectprognosis
dc.subjectsurvival rate
dc.titleRetrospective evaluation of patients diagnosed solid pseudopapillary neoplasms of the pancreas
dc.typeArticle

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