Does a patient-specific bladder-filling protocol affect bladder volume and dose in postprostatectomy radiotherapy?

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dc.contributor.authorYalman D.
dc.contributor.authorKöylü M.
dc.contributor.authorDuran Ö.
dc.date.accessioned2024-07-22T08:01:41Z
dc.date.available2024-07-22T08:01:41Z
dc.date.issued2024
dc.description.abstractPurpose: Our aim is to develop a patient-specific bladder-filling protocol (PSP) using an ultrasound-based bladder scanner (BS) and compare the volumetric and dosimetric parameters with those of the standard filling protocol (SP) in postprostatectomy patients. Methods: Twenty postprostatectomy patients who received salvage radiotherapy (72 Gy/36 fx) were included. For PSP, the patient was asked to drink 500 mL of water after emptying his bladder. Bladder volume was measured using BS every 10 min. Each patient's unique time to reach a 150–200 cc volume was used for simulation and treatment. For the SP, the patient was asked about the feeling of having a full bladder. Organs at risk (OAR) were contoured on cone-beam computed tomography (CBCT) scans that were transferred to the treatment planning system (TPS). Treatment plans were applied to CBCTs. Changes in bladder volume and doses for planning computed tomography (PCT) and CBCT were determined. Results: In the SP, there was no significant difference in mean bladder volume for PCT and CBCT (p = 0.139); however, there was a trend for significance in the mean bladder dose (p = 0.074). In PSP, there was no significant difference in the mean bladder volume or dose for PCT and CBCT (p = 0.139 and p = 0.799, respectively). There was a significant difference in terms of mean CBCT bladder volume between the two protocols (p = 0.007), whereas no significant difference was detected in terms of bladder dose (p = 0.130). Conclusion: With PSP, optimal bladder filling was obtained and maintained throughout the whole treatment course, and it was reproducible in every fraction. © The Author(s), under exclusive licence to Springer Nature B.V. 2023.
dc.identifier.DOI-ID10.1007/s11255-023-03814-8
dc.identifier.issn03011623
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11556
dc.language.isoEnglish
dc.publisherSpringer Science and Business Media B.V.
dc.subjectwater
dc.subjectArticle
dc.subjectbladder
dc.subjectbladder capacity
dc.subjectbladder dose
dc.subjectbladder emptying
dc.subjectbladder examination
dc.subjectbladder ultrasound
dc.subjectcancer radiotherapy
dc.subjectclinical article
dc.subjectclinical protocol
dc.subjectcone beam computed tomography
dc.subjectcontrolled study
dc.subjectdosimetry
dc.subjecthuman
dc.subjecthuman tissue
dc.subjectorgans at risk
dc.subjectpatient specific bladder filling protocol
dc.subjectpilot study
dc.subjectplanning computed tomography
dc.subjectpostoperative period
dc.subjectprostatectomy
dc.subjectradiation response
dc.subjectreproducibility
dc.subjectsalvage therapy
dc.subjectsimulation
dc.subjectstandard filling protocol
dc.subjecttreatment planning
dc.subjecttrend study
dc.subjectultrasound
dc.titleDoes a patient-specific bladder-filling protocol affect bladder volume and dose in postprostatectomy radiotherapy?
dc.typeArticle

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