Venlafaxine in the treatment of depression in schizophrenia; [Şizofrenide depresyonun venlafaksinle saǧaltimi]

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dc.contributor.authorEsen-Danaci A.
dc.contributor.authorAydemir Ö.
dc.date.accessioned2024-07-22T08:23:21Z
dc.date.available2024-07-22T08:23:21Z
dc.date.issued2006
dc.description.abstractObjective: Depression in schizophrenia is associated with a poor outcome, an increased risk of relapse and a high rate of suicide therefore it must be treated carefully. Venlafaxine is a dual-action serotonin and noradrenergic reuptake inhibitor and is effective in treating depressive patients. Method: In this study the efficacy and tolerability of venlafaxine is evaluated in 8 schizophrenic patients with depression who used venlafaxine adjunctive to atypical antipsychotics. Results: The patients were assessed with Calgary Depression Scale for Schizophrenia (CDSS), Scale for the Assessment of Positive and Negative Symptoms (SAPS and SANS) at the beginning, 4th week and 8th week. At the end of 8th week of treatment, 2 patients were fully remitted, the other 4 patients showed 80-90% improvement. Total SAPS scores dropped 2 points whereas SANS scores were dropped by 25%. No patients had an adverse event leading to an intervention. Conclusion: Venlafaxine may be an effective and safe alternative in the treatment of depression in schizophrenia.
dc.identifier.issn13029657
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19472
dc.language.isoTurkish
dc.subjectatypical antipsychotic agent
dc.subjectvenlafaxine
dc.subjectabsence of side effects
dc.subjectarticle
dc.subjectclinical article
dc.subjectcontrolled study
dc.subjectdepression
dc.subjectdisease association
dc.subjectdrug efficacy
dc.subjecthuman
dc.subjectpatient assessment
dc.subjectprognosis
dc.subjectrelapse
dc.subjectrisk
dc.subjectschizophrenia
dc.subjectscoring system
dc.subjectsuicide
dc.subjectsymptomatology
dc.titleVenlafaxine in the treatment of depression in schizophrenia; [Şizofrenide depresyonun venlafaksinle saǧaltimi]
dc.typeArticle

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