Can Aortic and Renal Arteries Calcium Scores Be New Factors to Predict Post-Operative Renal Function After Nephron Sparing Surgery?

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dc.contributor.authorAkarken İ.
dc.contributor.authorBilen C.Y.
dc.contributor.authorÖzden E.
dc.contributor.authorGülşen M.
dc.contributor.authorÜçer O.
dc.contributor.authorŞahin H.
dc.date.accessioned2024-07-22T08:04:42Z
dc.date.available2024-07-22T08:04:42Z
dc.date.issued2022
dc.description.abstractIntroduction: This study aims to investigate whether the calcification of renal arteries and aorta may be risk factors for developing chronic kidney disease (CKD) after Nephron sparing surgery (NSS). Materials and Methods: The patients that underwent either open or laparoscopic NSS from 2000 to 2019 in 4 different centers were retrospectively assessed. Of these patients, 328 had a non-contrast-enhanced computer tomography. Calcium scores of the renal arteries and abdominal aorta were measured in the non-contrast-enhanced images with the calcium score plugin (version 2.0) of Horos™. Univariate and multivariate logistic regression analysis was performed to determine significant risk factors for developing CKD at the last check-up. Roc curve analysis was performed to determine the optimal cut-off values of age and abdominal aorta calcium scores. Results: A total of 302 patients, of which 52 (16,6%) with CKD and 252 (83,4%) without CKD at the last check-up, were included in the analysis. The mean warm ischemia duration was significantly higher in patients with CKD (18,79±6,72 vs 16,38±5,57 minutes, p=0,016). The mean size of the tumor diameter and the number of the patients with ≥stage T1b were higher in the group with CKD (p=0,024 and 0,005, respectively). The median calcium scores of the aorta and renal arteries were higher in the group with CKD (p<0,001 and p<0,001, respectively). In multivariate analysis, age >60 years (OR:3,65, p=0,022), calcium score of the aorta (OR:4,07, p=0,029), tumor diameter (OR:1,03, p=0,026) and pre-operative CKD stage (OR:10,13, p<0,001) found the be significant factors for predicting last check-up CKD. Conclusion: The calcium score of the aorta may be used as an additional risk factor to predict post-operative CKD risk after NSS with sensitivity over 80%. © 2021
dc.identifier.DOI-ID10.1016/j.clgc.2021.09.002
dc.identifier.issn15587673
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/12800
dc.language.isoEnglish
dc.publisherElsevier Inc.
dc.subjectAorta
dc.subjectCalcium
dc.subjectFemale
dc.subjectHumans
dc.subjectKidney
dc.subjectKidney Neoplasms
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectNephrectomy
dc.subjectNephrons
dc.subjectRenal Artery
dc.subjectRenal Insufficiency, Chronic
dc.subjectRetrospective Studies
dc.subjectcalcium
dc.subjectabdominal aorta
dc.subjectabdominal aorta calcium score
dc.subjectadult
dc.subjectaortic calcification
dc.subjectartery calcification
dc.subjectArticle
dc.subjectcalcification
dc.subjectcancer size
dc.subjectcardiovascular parameters
dc.subjectchronic kidney failure
dc.subjectclinical practice
dc.subjectcohort analysis
dc.subjectcomputer assisted tomography
dc.subjectfemale
dc.subjectfollow up
dc.subjectgold standard
dc.subjecthuman
dc.subjectkidney artery
dc.subjectkidney artery calcium score
dc.subjectkidney function
dc.subjectlaparoscopic surgery
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmultivariate logistic regression analysis
dc.subjectnephron sparing surgery
dc.subjectopen surgery
dc.subjectoperation duration
dc.subjectpostoperative period
dc.subjectreceiver operating characteristic
dc.subjectreference value
dc.subjectretrospective study
dc.subjectwarm ischemia time
dc.subjectadverse event
dc.subjectaorta
dc.subjectchronic kidney failure
dc.subjectdiagnostic imaging
dc.subjectkidney
dc.subjectkidney artery
dc.subjectkidney tumor
dc.subjectmiddle aged
dc.subjectnephrectomy
dc.subjectnephron
dc.subjectpathology
dc.subjectphysiology
dc.subjectprocedures
dc.subjectsurgery
dc.titleCan Aortic and Renal Arteries Calcium Scores Be New Factors to Predict Post-Operative Renal Function After Nephron Sparing Surgery?
dc.typeArticle

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