Pandemic of the century: COVID-19 in inflammatory rheumatic diseases of a national cohort with 3,532 patients

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dc.contributor.authorYurdakul F.
dc.contributor.authorBodur H.
dc.contributor.authorCengiz A.K.
dc.contributor.authorDurmaz Y.
dc.contributor.authorDuruöz M.T.
dc.contributor.authorKaya T.
dc.contributor.authorKetenci S.
dc.contributor.authorCüzdan N.
dc.contributor.authorGüler T.
dc.contributor.authorGünendi Z.
dc.contributor.authorSarıkaya S.
dc.contributor.authorÇapkın E.
dc.contributor.authorÖnder M.E.
dc.contributor.authorMelikoğlu M.A.
dc.contributor.authorGüzel R.
dc.contributor.authorŞen N.
dc.contributor.authorAyna A.B.
dc.contributor.authorAkgül Ö.
dc.contributor.authorEser E.
dc.contributor.authorAtaman Ş.
dc.date.accessioned2024-07-22T08:01:09Z
dc.date.available2024-07-22T08:01:09Z
dc.date.issued2024
dc.description.abstractObjectives: This study aimed to assess the clinical outcomes and risk factors for severe coronavirus disease 2019 (COVID-19) in patients with inflammatory rheumatic disease (IRD) of a national cohort. Patients and methods: The multicenter cross-sectional study was carried out between July 15, 2020, and February 28, 2021. Data collection was provided from a national network database system, and 3,532 IRD patients (2,359 males, 1,173 females; mean age: 48.7±13.9 years; range; 18 to 90 years) were analyzed. Demographics, clinics about rheumatic disease, comorbidities, smoking status, being infected with COVID-19, and the course of the infection were questioned by rheumatology specialists. Results: One hundred seventeen patients were infected with COVID-19, the hospitalization rate due to COVID-19 was 58.9%, and the mortality rate was 1.7%. There was no difference between the COVID-19 positive and negative groups in terms of rheumatic disease activities and receiving drugs. It was observed that patients with COVID-19 had worse compliance with isolation rules, and bacillus Calmette-Guérin (BCG) vaccination was less common. The mean age and the rate of smoking of hospitalized COVID-19 patients were higher than those without hospitalization. Conclusion: In this cohort, in which real-life data were analyzed, COVID-19 rates in IRD patients were similar to the general population for the same period. Compliance with the isolation rules and BCG vaccination attracted attention as components that reduce the risk of COVID-19 infection. The risk factors for hospitalization were older age and smoking. © 2024, Turkish League Against Rheumatism (TLAR). All rights reserved.
dc.identifier.DOI-ID10.46497/archrheumatol.2024.10313
dc.identifier.issn26186500
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/11347
dc.language.isoEnglish
dc.publisherTurkish League Against Rheumatism (TLAR)
dc.rightsAll Open Access; Gold Open Access
dc.subjectCD20 antibody
dc.subjectcyclophosphamide
dc.subjectcyclosporine
dc.subjectcytokine receptor antagonist
dc.subjectdisease modifying antirheumatic drug
dc.subjectglucocorticoid
dc.subjecthydroxychloroquine
dc.subjectimmunoglobulin
dc.subjectJanus kinase inhibitor
dc.subjectleflunomide
dc.subjectmethotrexate
dc.subjectmycophenolic acid
dc.subjectsalazosulfapyridine
dc.subjecttumor necrosis factor inhibitor
dc.subjectadult
dc.subjectadult respiratory distress syndrome
dc.subjectaged
dc.subjectArticle
dc.subjectBCG vaccination
dc.subjectcohort analysis
dc.subjectcomorbidity
dc.subjectcontrolled study
dc.subjectcoronavirus disease 2019
dc.subjectcross-sectional study
dc.subjectfamilial Mediterranean fever
dc.subjectfemale
dc.subjecthospitalization
dc.subjecthuman
dc.subjectinflammation
dc.subjectmacrophage activation syndrome
dc.subjectmale
dc.subjectpandemic
dc.subjectrheumatic disease
dc.subjectsepsis
dc.subjectsmoking
dc.subjectthromboembolism
dc.titlePandemic of the century: COVID-19 in inflammatory rheumatic diseases of a national cohort with 3,532 patients
dc.typeArticle

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