Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018 population-based measurement studies with 88.6 million participants

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dc.date.accessioned2024-07-22T08:09:47Z
dc.date.available2024-07-22T08:09:47Z
dc.date.issued2018
dc.description.abstractBackground: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure. Methods: We pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean diastolic blood pressure (DBP) and prevalence of raised blood pressure by sex and 10-year age group from 20-29 years to 70-79 years in each study, taking into account complex survey design and survey sample weights, where relevant. We used a linear mixed effect model to quantify the association between (probittransformed) prevalence of raised blood pressure and age-group- and sex-specific mean blood pressure. We calculated the contributions of change in mean SBP and DBP, and of change in the prevalence-mean association, to the change in prevalence of raised blood pressure. Results: In 2005-16, at the same level of population mean SBP and DBP, men and women in South Asia and in Central Asia, the Middle East and North Africa would have the highest prevalence of raised blood pressure, and men and women in the highincome Asia Pacific and high-income Western regions would have the lowest. In most region-sex-age groups where the prevalence of raised blood pressure declined, one half or more of the decline was due to the decline in mean blood pressure. Where prevalence of raised blood pressure has increased, the change was entirely driven by increasing mean blood pressure, offset partly by the change in the prevalence-mean association. Conclusions: Change in mean blood pressure is the main driver of the worldwide change in the prevalence of raised blood pressure, but change in the high-blood-pressure tail of the distribution has also contributed to the change in prevalence, especially in older age groups. © The Author(s) 2018.
dc.identifier.DOI-ID10.1093/ije/dyy016
dc.identifier.issn03005771
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/14963
dc.language.isoEnglish
dc.publisherOxford University Press
dc.rightsAll Open Access; Hybrid Gold Open Access
dc.subjectCentral Asia
dc.subjectMiddle East
dc.subjectNorth Africa
dc.subjectPacific Ocean
dc.subjectPacific Rim
dc.subjectSouth Asia
dc.subjectblood
dc.subjectdisease prevalence
dc.subjecthealth survey
dc.subjectmeasurement method
dc.subjectpublic health
dc.subjectsurvey design
dc.subjecttrend analysis
dc.subjectadult
dc.subjectaged
dc.subjectArticle
dc.subjectblood pressure measurement
dc.subjectblood pressure regulation
dc.subjectdiastolic blood pressure
dc.subjectfemale
dc.subjectglobal health
dc.subjecthigh income country
dc.subjecthuman
dc.subjecthypertension
dc.subjectlow income country
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmean arterial pressure
dc.subjectmiddle income country
dc.subjectpopulation health
dc.subjectpopulation research
dc.subjectprevalence
dc.subjectpriority journal
dc.subjectsystolic blood pressure
dc.subjecttrend study
dc.titleContributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018 population-based measurement studies with 88.6 million participants
dc.typeArticle

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