Recreational and master athletic activity does not affect free and total prostate-specific antigen levels but lowers the free-to-total prostate-specific antigen ratio

dc.contributor.authorUlman C.
dc.contributor.authorBuyukyazi G.
dc.contributor.authorTaneli F.
dc.contributor.authorUyanik B.S.
dc.date.accessioned2024-07-22T08:24:36Z
dc.date.available2024-07-22T08:24:36Z
dc.date.issued2004
dc.description.abstractProstate-specific antigen (PSA) and the ratio of free-to-total PSA are widely used tumour markers, but the effect of exercise on these parameters is unclear. We aimed to determine whether long-term physical training was associated with changes in serum PSA by comparing PSA concentrations in middle-aged master athletes (n = 12), recreational athletes (n = 12) and sedentary controls (n = 12). Serum total PSA and free PSA concentrations were assessed using an electrochemiluminescence immunoassay; there were no significant differences among the groups. The free-to-total PSA ratio was significantly lower statistically in master athletes compared with recreational athletes, but this is not clinically significant as both values (0.22 versus 0.31, respectively) were within the normal range. These results indicate that the free-to-total PSA ratio may be affected by long-term athletic training, and could be important when evaluating athletes with prostate-related disorders.
dc.identifier.DOI-ID10.1177/147323000403200603
dc.identifier.issn03000605
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/20051
dc.language.isoEnglish
dc.publisherCambridge Medical Publications
dc.subjectprostate specific antigen
dc.subjectadult
dc.subjectarticle
dc.subjectathlete
dc.subjectblood level
dc.subjectchemoluminescence
dc.subjectcontrolled study
dc.subjectelectrochemical analysis
dc.subjectevaluation
dc.subjecthuman
dc.subjecthuman experiment
dc.subjectimmunoassay
dc.subjectmale
dc.subjectnormal value
dc.subjectphysical activity
dc.subjectprostate disease
dc.subjectrecreation
dc.subjectsitting
dc.subjectsport
dc.subjectstatistical significance
dc.subjecttime
dc.subjecttraining
dc.titleRecreational and master athletic activity does not affect free and total prostate-specific antigen levels but lowers the free-to-total prostate-specific antigen ratio
dc.typeArticle

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