Determination of oleuropein using multiwalled carbon nanotube modified glassy carbon electrode by adsorptive stripping square wave voltammetry

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dc.contributor.authorCittan M.
dc.contributor.authorKoçak S.
dc.contributor.authorÇelik A.
dc.contributor.authorDost K.
dc.date.accessioned2024-07-22T08:11:38Z
dc.date.available2024-07-22T08:11:38Z
dc.date.issued2016
dc.description.abstractA multi-walled carbon nanotube modified glassy carbon electrode was used to prepare an electrochemical sensing platform for the determination of oleuropein. Results showed that, the accumulation of oleuropein on the prepared electrode takes place with the adsorption process. Electrochemical behavior of oleuropein was studied by using cyclic voltammetry. Compared to the bare GCE, the oxidation peak current of oleuropein increased about 340 times at MWCNT/GCE. Voltammetric determination of oleuropein on the surface of prepared electrode was studied using square wave voltammetry where the oxidation peak current of oleuropein was measured as an analytical signal. A calibration curve of oleuropein was performed between 0.01 and 0.70 μM and a good linearity was obtained with a correlation coefficient of 0.9984. Detection and quantification limits of the method were obtained as 2.73 and 9.09 nM, respectively. In addition, intra-day and inter-day precision studies indicated that the voltammetric method was sufficiently repeatable. Finally, the proposed electrochemical sensor was successfully applied to the determination of oleuropein in an olive leaf extract. Microwave-assisted extraction of oleuropein had good recovery values between 92% and 98%. The results obtained with the proposed electrochemical sensor were compared with liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis. © 2016 Elsevier B.V.
dc.identifier.DOI-ID10.1016/j.talanta.2016.06.021
dc.identifier.issn00399140
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/15735
dc.language.isoEnglish
dc.publisherElsevier B.V.
dc.subjectAdsorption
dc.subjectCyclic voltammetry
dc.subjectDrug products
dc.subjectElectrochemical sensors
dc.subjectGlass
dc.subjectGlass membrane electrodes
dc.subjectLiquid chromatography
dc.subjectMass spectrometry
dc.subjectYarn
dc.subjectDetection and quantification limit
dc.subjectElectrochemical behaviors
dc.subjectLiquid chromatography tandem mass spectrometry (LC MS/MS)
dc.subjectMicrowave-assisted extraction
dc.subjectModified glassy carbon electrode
dc.subjectOleuropein
dc.subjectSquare wave voltammetry
dc.subjectVoltammetric determination
dc.subjectMultiwalled carbon nanotubes (MWCN)
dc.titleDetermination of oleuropein using multiwalled carbon nanotube modified glassy carbon electrode by adsorptive stripping square wave voltammetry
dc.typeArticle

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