A physical model of the thermodilution method: Influences of the variations of experimental setup on the accuracy of flow rate estimation

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dc.contributor.authorÖzbek M.
dc.contributor.authorÖzel H.F.
dc.contributor.authorEkerbiçer N.
dc.contributor.authorZeren T.
dc.date.accessioned2024-07-22T08:20:26Z
dc.date.available2024-07-22T08:20:26Z
dc.date.issued2011
dc.description.abstractThe thermodilution method has been widely used to estimate cardiac output by injecting a cold solution into circulating blood. It is uncertain if radial heat transfer from the vascular/cardiac wall to circulating injectate can cause inaccurate results with this method. In this study, we have introduced a physical experimental model of the thermodilution method without recirculation of the cold solution. To test the accuracy of the thermodilution method, the experimental setup included an aluminum tube to allow radial heat transfer. Variations of the following parameters were conducted: (i) the real flow rate, (ii) the distance between injection point of cold solution and the temperature sensor, (iii) the volume of injectate, and (iv) the temperature of injectate. By following the above variations, we have calculated different correction factors eliminating the influence of radial heat transfer on the estimation of flow rate by the thermodilution method. The results indicate that changes in both injectate temperature and volume have no influence on the estimation of flow rates. The experimental variations, which can cause greater radial heat transfer, seem to be responsible for the result of the smaller estimation of the flow rate than the real value. These variations include (i) a decreased real flow rate and (ii) increased distances between the injection point of cold fluid and the thermosensor. Such an incorrect estimation could be eliminated by using correction factors. The correction factor seems to be a function of the area of the thermodilution curve, assuming no recirculation. © 2011 by Walter de Gruyter Berlin New York.
dc.identifier.DOI-ID10.1515/BMT.2010.058
dc.identifier.issn00135585
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18158
dc.language.isoEnglish
dc.subjectAnimals
dc.subjectBlood Flow Velocity
dc.subjectBlood Physiological Phenomena
dc.subjectCardiac Output
dc.subjectComputer Simulation
dc.subjectHumans
dc.subjectModels, Cardiovascular
dc.subjectReproducibility of Results
dc.subjectRheology
dc.subjectSensitivity and Specificity
dc.subjectThermodilution
dc.subjectHeat transfer
dc.subjectHemodynamics
dc.subjectAluminum tubes
dc.subjectCardiac output
dc.subjectCold fluid
dc.subjectCorrection factors
dc.subjectExperimental models
dc.subjectExperimental setup
dc.subjectPhysical model
dc.subjectRadial heat transfer
dc.subjectRate estimation
dc.subjectReal flow
dc.subjectReal values
dc.subjectRecirculations
dc.subjectThermo-sensor
dc.subjectThermodilution
dc.subjectanimal
dc.subjectarticle
dc.subjectbiological model
dc.subjectblood flow velocity
dc.subjectcomputer simulation
dc.subjectflow kinetics
dc.subjectfunctions of the hemic, lymphatic and reticuloendothelial systems
dc.subjectheart output
dc.subjecthuman
dc.subjectmethodology
dc.subjectphysiology
dc.subjectreproducibility
dc.subjectsensitivity and specificity
dc.subjectthermodilution
dc.subjectEstimation
dc.titleA physical model of the thermodilution method: Influences of the variations of experimental setup on the accuracy of flow rate estimation
dc.typeArticle

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