Oh my aching gut: Irritable bowel syndrome, Blastocystis, and asymptomatic infection

Simple item page
dc.contributor.authorBoorom K.F.
dc.contributor.authorSmith H.
dc.contributor.authorNimri L.
dc.contributor.authorViscogliosi E.
dc.contributor.authorSpanakos G.
dc.contributor.authorParkar U.
dc.contributor.authorLi L.-H.
dc.contributor.authorZhou X.-N.
dc.contributor.authorOk L.Z.
dc.contributor.authorLeelayoova S.
dc.contributor.authorJones M.S.
dc.date.accessioned2024-07-22T08:22:03Z
dc.date.available2024-07-22T08:22:03Z
dc.date.issued2008
dc.description.abstractBlastocystis is a prevalent enteric protozoan that infects a variety of vertebrates. Infection with Blastocystis in humans has been associated with abdominal pain, diarrhea, constipation, fatigue, skin rash, and other symptoms. Researchers using different methods and examining different patient groups have reported asymptomatic infection, acute symptomatic infection, and chronic symptomatic infection. The variation in accounts has lead to disagreements concerning the role of Blastocystis in human disease, and the importance of treating it. A better understanding of the number of species of Blastocystis that can infect humans, along with realization of the limitations of the existing clinical laboratory diagnostic techniques may account for much of the disagreement. The possibility that disagreement was caused by the emergence of particular pathogenic variants of Blastocystis is discussed, along with the potential role of Blastocystis infection in irritable bowel syndrome (IBS). Findings are discussed concerning the role of protease-activated receptor-2 in enteric disease which may account for the presence of abdominal pain and diffuse symptoms in Blastocystis infection, even in the absence of fever and endoscopic findings. The availability of better diagnostic techniques and treatments for Blastocystis infection may be of value in understanding chronic gastrointestinal illness of unknown etiology.
dc.identifier.DOI-ID10.1186/1756-3305-1-40
dc.identifier.issn17563305
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18884
dc.language.isoEnglish
dc.rightsAll Open Access; Gold Open Access; Green Open Access
dc.subjectBlastocystis
dc.subjectProtozoa
dc.subjectVertebrata
dc.subjectalbendazole
dc.subjectcotrimoxazole
dc.subjectdiiodohydroxyquin
dc.subjectdoxycycline
dc.subjectfurazolidone
dc.subjectitraconazole
dc.subjectketoconazole
dc.subjectmepacrine
dc.subjectmetronidazole
dc.subjectnitazoxanide
dc.subjectornidazole
dc.subjectparomomycin
dc.subjectproteinase activated receptor 2
dc.subjectrifaximin
dc.subjectsecnidazole
dc.subjecttinidazole
dc.subjectabdominal pain
dc.subjectarticle
dc.subjectasymptomatic infection
dc.subjectBlastocystis
dc.subjectblastocystosis
dc.subjectconstipation
dc.subjectdiagnostic accuracy
dc.subjectdiagnostic test
dc.subjectdiarrhea
dc.subjectfatigue
dc.subjecthuman
dc.subjectinfection
dc.subjectirritable colon
dc.subjectnonhuman
dc.subjectprevalence
dc.subjectrash
dc.subjectsymptom
dc.titleOh my aching gut: Irritable bowel syndrome, Blastocystis, and asymptomatic infection
dc.typeArticle

Files

Collections

Scopus Koleksiyonu