Mitochondrial dysfunction particularly in adipocytes may be an important triggering factor for type 2 diabetes
Abstract
[No abstract available]
Description
Keywords
Adipocytes , Diabetes Mellitus, Type 2 , Humans , Lipid Metabolism , Mitochondria , Mitochondrial Diseases , Models, Biological , adenosine triphosphate , DNA , glucose transporter , peroxisome proliferator activated receptor gamma coactivator 1alpha , reactive oxygen metabolite , superoxide , uncoupling protein 2 , adipocyte , cell metabolism , diabetic patient , disease course , disorders of mitochondrial functions , energy metabolism , exercise , fatty acid oxidation , gene expression , gene mutation , gene overexpression , glucose homeostasis , glucose tolerance , hyperglycemia , impaired glucose tolerance , insulin release , letter , lipid metabolism , mitochondrial DNA depletion , mitochondrial respiration , non insulin dependent diabetes mellitus , nonhuman , obesity , oxidative phosphorylation , oxidative stress , pancreas islet beta cell , pathophysiology , priority journal