Netherton's syndrome: An ultrastructural study: Case report; [Netherton sendromu: Elektron mikroskobik çalışma]

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dc.contributor.authorÖztürkcan S.
dc.contributor.authorInan S.
dc.contributor.authorŞahin M.T.
dc.contributor.authorErmertcan A.T.
dc.contributor.authorGüzel E.E.
dc.contributor.authorMüftüoǧlu S.
dc.date.accessioned2024-07-22T08:21:16Z
dc.date.available2024-07-22T08:21:16Z
dc.date.issued2010
dc.description.abstractHair samples taken from 12-year-old boy prediagnosed with Netherton's syndrome were evaluated by using light and electron microscopic methods. Hair samples were prepared according to routine electron microscopic procedures. Semi-thin sections were stained with methylene blue-azure II, thin sections were contrasted with uranyl acetate-lead citrate. Besides atopy symptoms, hyperparakeratosis and inflammatory cell infiltration were seen in dermis. Results were in accordance with icthyosis linearis circumflexa. In cortex portion of hair, nodulary thickening and swelling were observed. There was a punctured proximal portion like a telescope in distal hair shaft segment. Cells that make up hair cortex were seen to be loosely arranged and there was detachment between cells exterior of cuticle. In evaluating all results trichorrhexis invaginata was identified. Patients given long term therapy for atopic dermatitis, which have breaking of hair in addition to icthyosis, Netherton's syndrome should be thought and investigation of hair samples for supporting the diagnosis is important. © 2010 by Türkiye Klinikleri.
dc.identifier.DOI-ID10.5336/medsci.2008-9387
dc.identifier.issn13000292
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18543
dc.language.isoTurkish
dc.publisherTurkiye Klinikleri
dc.rightsAll Open Access; Green Open Access; Hybrid Gold Open Access
dc.subjectmethylene blue
dc.subjecturanyl acetate
dc.subjectarticle
dc.subjectatopy
dc.subjectcase report
dc.subjectcell infiltration
dc.subjectchild
dc.subjectclinical feature
dc.subjectdermis
dc.subjectelectron microscopy
dc.subjecthair analysis
dc.subjecthair cell
dc.subjecthuman
dc.subjecthyperkeratosis
dc.subjectinflammatory cell
dc.subjectlamellar ichthyosis
dc.subjectmale
dc.subjectmicroscopy
dc.subjectNetherton disease
dc.subjectschool child
dc.subjecttrichorrhexis
dc.titleNetherton's syndrome: An ultrastructural study: Case report; [Netherton sendromu: Elektron mikroskobik çalışma]
dc.typeArticle

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