Premedication during micturating cystourethrogram to achieve sedation and anxiolysis

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dc.contributor.authorAkil I.
dc.contributor.authorOzkol M.
dc.contributor.authorIkizoglu O.Y.
dc.contributor.authorPolat M.
dc.contributor.authorTuncyurek O.Y.
dc.contributor.authorTaskin O.
dc.contributor.authorYuksel H.
dc.date.accessioned2024-07-22T08:23:51Z
dc.date.available2024-07-22T08:23:51Z
dc.date.issued2005
dc.description.abstractMicturating cystourethrogram (MCUG) is an imaging technique indicated in the diagnosis and follow-up of many diseases. We investigated the reliability and the efficacy of midazolam and chloral hydrate in sedation and anxiolysis during micturating cystourethrogram. Fifty-three children of similar ages (39 girls, 14 boys, mean age of 5.8±3.5 years) were randomized to midazolam (n=17), chloral hydrate (n=18) and control groups (n=18). Oral midazolam 0.6 mg/kg or chloral hydrate 25 mg/kg or saline were administered to the study groups 15-30 min prior to the urinary catheterization. Brietkopf and Buttner, Frankl and Houpt scales and Spielberger's State Anxiety Inventory and parent's impressions were used to assess the level of sedation and anxiety. The Brietkopf and Buttner classification of emotional status and Houpt behavior rating scale demonstrated a significantly better emotional status and sedation in the midazolam group when compared to controls (P=0.01 and P=0.018, respectively). The catheterization was described as a more unpleasant and distressing event by the parents of the control and the chloral hydrate groups when compared to the parents of the midazolam group (P<0.05). Bladder capacity and frequency of detection of residual urine were not statistically different between the three study groups (P>0.05). Vital signs did not change significantly in any child. Sedation with midazolam does not have adverse effects on the results of micturating cystourethrogram, while it reduces the discomfort in children undergoing this radiological technique. © IPNA 2005.
dc.identifier.DOI-ID10.1007/s00467-005-1874-0
dc.identifier.issn0931041X
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19726
dc.language.isoEnglish
dc.subjectAnti-Anxiety Agents
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectChloral Hydrate
dc.subjectFemale
dc.subjectHumans
dc.subjectHypnotics and Sedatives
dc.subjectInfant
dc.subjectMale
dc.subjectMidazolam
dc.subjectPremedication
dc.subjectUrethra
dc.subjectUrinary Bladder
dc.subjectUrography
dc.subjectchloral hydrate
dc.subjectmidazolam
dc.subjectsodium chloride
dc.subjectadolescent
dc.subjectarticle
dc.subjectbladder capacity
dc.subjectcatheterization
dc.subjectchild
dc.subjectclinical trial
dc.subjectcontrolled clinical trial
dc.subjectcontrolled study
dc.subjectdrug efficacy
dc.subjectfemale
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmicturition cystourethrography
dc.subjectpediatric anesthesia
dc.subjectpremedication
dc.subjectpreoperative care
dc.subjectpriority journal
dc.subjectrandomized controlled trial
dc.subjectrating scale
dc.subjectreliability
dc.subjectresidual urine
dc.subjectsedation
dc.subjectstate trait anxiety inventory
dc.subjectstatistical significance
dc.subjecttranquilizing activity
dc.subjecturinary frequency
dc.titlePremedication during micturating cystourethrogram to achieve sedation and anxiolysis
dc.typeArticle

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