Evaluation of scale-up methodologies and computational fluid dynamics simulation for fucoxanthin production in airlift photobioareactor

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dc.contributor.authorAslanbay Guler B.
dc.contributor.authorDeniz I.
dc.contributor.authorDemirel Z.
dc.contributor.authorImamoglu E.
dc.date.accessioned2024-07-22T08:07:07Z
dc.date.available2024-07-22T08:07:07Z
dc.date.issued2020
dc.description.abstractResearches about commercial-scale production of fucoxanthin are increasing day by day due to the much interest of its broad beneficial health effects. The aim of this study was to investigate the scale-up methodologies in airlift photobioreactor and to simulate fluid flow using computational fluid dynamics (CFD) for fucoxanthin production from Phaeodactylum tricornutum microalgae. During the transition process from 1-L cultivation bottle to the 2-L airlift photobioreactor, the constant mixing time, the constant volumetric oxygen transfer coefficient, and the constant volumetric power consumption rate were evaluated as scale-up methodologies under laboratory conditions. Maximum fucoxanthin yield was found as 1.01 ± 0.07 mg g−1 using scale-up strategy based on constant volumetric power consumption rate. After that, CFD simulation was performed in order to examine flow characteristics, mixing efficiency, hydrodynamics, and gas holdup for selected operation conditions. It was observed that mixing efficiency was low because the draft tube configuration prevented the circulation of fluid and caused a heterogenic culture medium inside the reactor. It is possible to overcome this bottleneck by developing the effective draft tube. © 2020 Curtin University and John Wiley & Sons, Ltd.
dc.identifier.DOI-ID10.1002/apj.2532
dc.identifier.issn19322135
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13843
dc.language.isoEnglish
dc.publisherJohn Wiley and Sons Ltd
dc.subjectBottles
dc.subjectEfficiency
dc.subjectElectric power utilization
dc.subjectFlow of fluids
dc.subjectMixing
dc.subjectPhotobioreactors
dc.subjectAirlift photobioreactor
dc.subjectCommercial-scale production
dc.subjectComputational fluid dynamics simulations
dc.subjectFlow charac-teristics
dc.subjectLaboratory conditions
dc.subjectPhaeodactylum tricornutum
dc.subjectVolumetric oxygen transfer coefficient
dc.subjectVolumetric power consumption
dc.subjectComputational fluid dynamics
dc.titleEvaluation of scale-up methodologies and computational fluid dynamics simulation for fucoxanthin production in airlift photobioareactor
dc.typeArticle

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