Evaluation of maternal renal cortical elasticity in pregnancies with early- and late-onset preeclampsia

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dc.contributor.authorAkbas M.
dc.contributor.authorKoyuncu F.M.
dc.date.accessioned2024-07-22T08:07:32Z
dc.date.available2024-07-22T08:07:32Z
dc.date.issued2020
dc.description.abstractObjective: The current study aimed to investigate renal cortical elasticity (RCE) in early- and late-onset preeclampsia patients and compare the results with healthy controls. Materials and methods: The study consisted of 136 pregnant women. Three groups were identified as; the late-onset preeclampsia (LOP) group (n = 40), the early-onset preeclampsia (EOP) group (n = 32) and the control group (n = 64). RCE values were measured by point shear wave elastography (pSWE). Nine measurements were taken for each kidney and the mean of nine measurements was accepted as the mean RCE value for each kidney. The arithmetic mean of left and right RCE values was accepted as the overall RCE value of a subject. Groups were compared in terms of clinical and biochemical parameters, ultrasonography findings and pSWE values. Results: There was a statistically significant difference between groups in terms of overall RCE values (F[2,133] = 17.96, p <.001). Post hoc comparisons indicated that both preeclampsia groups exhibited significantly higher RCE values than the control group. However, overall RCE values were not significantly different between the EOP and LOP groups. Overall RCE values were significantly and positively correlated with systolic blood pressure (r = 0.363, p <.001), diastolic blood pressure (r = 0.347, p <.001), proteinuria (r = 0.343, p <.001), serum creatinine level (r = 0.181, p =.035), serum uric acid level (r = 0.243, p =.004) and blood urea nitrogen (r = 0.27, p =.001). Conclusion: Our study demonstrated that maternal renal cortical stiffness increased in women with preeclampsia. The increased RCE values may be indicative for the severity of preeclampsia due to positive correlations between renal cortical stiffness and systolic–diastolic blood pressure and serum creatinine level. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.
dc.identifier.DOI-ID10.1080/14767058.2019.1671347
dc.identifier.issn14767058
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/13972
dc.language.isoEnglish
dc.publisherTaylor and Francis Ltd
dc.subjectAdult
dc.subjectBlood Pressure
dc.subjectCase-Control Studies
dc.subjectCreatinine
dc.subjectElasticity
dc.subjectElasticity Imaging Techniques
dc.subjectFemale
dc.subjectHumans
dc.subjectKidney
dc.subjectPre-Eclampsia
dc.subjectPregnancy
dc.subjectUltrasonography, Doppler
dc.subjectYoung Adult
dc.subjectcreatinine
dc.subjecturic acid
dc.subjectcreatinine
dc.subjectadult
dc.subjectArticle
dc.subjectbiochemistry
dc.subjectcorrelational study
dc.subjectcreatinine blood level
dc.subjectdiastolic blood pressure
dc.subjectDoppler ultrasonography
dc.subjectearly onset preeclampsia
dc.subjectelasticity
dc.subjectelastography
dc.subjectfemale
dc.subjectgray scale echography
dc.subjecthuman
dc.subjectkidney cortex
dc.subjectlate onset disorder
dc.subjectlate onset preeclampsia
dc.subjectmajor clinical study
dc.subjectmulticenter study
dc.subjectpreeclampsia
dc.subjectpregnancy
dc.subjectpregnant woman
dc.subjectpriority journal
dc.subjectproteinuria
dc.subjectsystolic blood pressure
dc.subjecturea nitrogen blood level
dc.subjecturic acid blood level
dc.subjectblood
dc.subjectblood pressure
dc.subjectcase control study
dc.subjectclassification
dc.subjectdiagnostic imaging
dc.subjectkidney
dc.subjectpathophysiology
dc.subjectpreeclampsia
dc.subjectpregnancy
dc.subjectyoung adult
dc.titleEvaluation of maternal renal cortical elasticity in pregnancies with early- and late-onset preeclampsia
dc.typeArticle

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