Population standards of prostate specific antigen values in men over 40: Community based study in Turkey

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dc.contributor.authorMüezzinoǧlu T.
dc.contributor.authorLekili M.
dc.contributor.authorEser E.
dc.contributor.authorUyanik B.S.
dc.contributor.authorBüyüksu C.
dc.date.accessioned2024-07-22T08:23:53Z
dc.date.available2024-07-22T08:23:53Z
dc.date.issued2005
dc.description.abstractObjective: To determine the prostate specific antigen (PSA) population standards of a cluster of Turkish men with no clinical evidence of prostate cancer. Patients and methods: We evaluated PSA values of the men who were living in a well-defined, rural district of Western Anatolia. Two hundred fifty-seven men agreed to participate in this population-based study. They underwent clinical examination, transrectal ultrasonography and serum PSA measurement. The association between serum PSA and age, prostate volume and age, PSA and prostate volume, and PSA density (PSAD) and age were assessed. Distributions of serum PSA levels, prostate volumes (PV), and PSAD values as a function of age were generated. Results: The upper limit of normal PSA concentration were 4.51 ng/ml for men aged 40-49 years, 4.36 ng/ml for 50-59 years, 6.17 ng/ml for 60-69 years, and 10.18 ng/ml for over 70 years. The upper limit of normal (95th percentile) for the serum PSA concentration increased with age. Across the entire age range, no correlation was found between the serum PSA concentrations and age while significant correlation was found between serum PSA concentration and prostate volume. Conclusion: In this present study, the PSA values in different age intervals showed higher than those observed in previous studies. The PSA values are mainly affected by prostate volume rather than age. © Springer 2005.
dc.identifier.DOI-ID10.1007/s11255-004-7976-y
dc.identifier.issn03011623
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/19740
dc.language.isoEnglish
dc.subjectAdult
dc.subjectAge Distribution
dc.subjectAged
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectProstate-Specific Antigen
dc.subjectReference Values
dc.subjectTurkey
dc.subjectprostate specific antigen
dc.subjectadult
dc.subjectaged
dc.subjectarticle
dc.subjectblood level
dc.subjectclinical examination
dc.subjectcluster analysis
dc.subjectcommunity care
dc.subjectcontrolled study
dc.subjectcorrelation function
dc.subjectdensity
dc.subjectgroups by age
dc.subjecthuman
dc.subjecthuman experiment
dc.subjectmale
dc.subjectmeasurement
dc.subjectnormal human
dc.subjectpopulation research
dc.subjectprostate cancer
dc.subjectrural area
dc.subjectstandardization
dc.subjectstatistical significance
dc.subjecttransrectal ultrasonography
dc.subjectTurkey (republic)
dc.subjectvolumetry
dc.titlePopulation standards of prostate specific antigen values in men over 40: Community based study in Turkey
dc.typeArticle

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