Gastric metastasis of merkel cell carcinoma: Case report; [Midede merkel hücreli karsinom metastazı: Olgu sunumu]

dc.contributor.authorTemiz P.
dc.contributor.authorAyhan S.
dc.contributor.authorAdigüzel L.
dc.contributor.authorKara E.
dc.contributor.authorOkçu G.
dc.date.accessioned2024-07-22T08:21:15Z
dc.date.available2024-07-22T08:21:15Z
dc.date.issued2010
dc.description.abstractMerkel cell carcinoma (MCC) of skin is a rare tumor with aggressive behavior. Local recurrences, regional lymph node and distant metastases of MCC are frequent but to date metastasis to upper gastrointestinal tract was reported only a few. We present a 75-yearold man who had primary MCC at his left thigh. The tumor was excised and the patient was directed to local radiotherapy. He had developed abdominal and thoracal subcutaneous metastatic nodules within 5 and 8 months after surgical excision, respectively. In the tenth month, a second operation had to be performed because of a perforated duodenal ulcer and incidentally a submucosal yellow-white nodule measuring 2 cm in diameter was found in the wall of gastric cardia and excised. This lesion was histologically identical to the primary tumor, hence, gastric metastasis of MCC. The patient rejected further therapy and died 17 months after the initial diagnosis. Differential diagnosis of MCC and distinction of gastrointestinal MCC metastasis from primary neuroendocrine tumors may be difficult. Clinical information and histopathological features along with the results of immunohistochemical stainings are very important in this distinction. © Medical Journal of Trakya University. Published by Ekin Medical Publishing. All rights reserved.
dc.identifier.DOI-ID10.5174/tutfd.2008.01093.2
dc.identifier.issn13013149
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/18530
dc.language.isoTurkish
dc.publisherEkin Tibbi Yayincilik
dc.rightsAll Open Access; Bronze Open Access; Green Open Access
dc.subjectchromogranin
dc.subjectenolase
dc.subjectaged
dc.subjectarticle
dc.subjectcase report
dc.subjectcytoplasm
dc.subjectduodenum ulcer
dc.subjecteosinophil
dc.subjectgastric metastasis
dc.subjectgastrostomy
dc.subjecthistopathology
dc.subjecthuman
dc.subjecthuman cell
dc.subjecthuman tissue
dc.subjectimmunohistochemistry
dc.subjectlamina propria
dc.subjectlung metastasis
dc.subjectmale
dc.subjectMerkel cell tumor
dc.subjectmitosis
dc.subjectsmall cell sarcoma
dc.subjectstomach mucosa
dc.subjecttumor cell
dc.subjecttumor volume
dc.subjectvisceral metastasis
dc.titleGastric metastasis of merkel cell carcinoma: Case report; [Midede merkel hücreli karsinom metastazı: Olgu sunumu]
dc.typeArticle

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