Mortality indicators in community-acquired pneumonia requiring intensive care in Turkey
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Date
2013
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Abstract
Background: Severe community-acquired pneumonia (SCAP) is a fatal disease. This study was conducted to describe an outcome analysis of the intensive care units (ICUs) of Turkey. Methods: This study evaluated SCAP cases hospitalized in the ICUs of 19 different hospitals between October 2008 and January 2011. The cases of 413 patients admitted to the ICUs were retrospectively analyzed. Results: Overall 413 patients were included in the study and 129 (31.2%) died. It was found that bilateral pulmonary involvement (odds ratio (OR) 2.5, 95% confidence interval (CI) 1.1-5.7) and CAP PIRO score (OR 2, 95% CI 1.3-2.9) were independent risk factors for a higher in-ICU mortality, while arterial hypertension (OR 0.3, 95% CI 0.1-0.9) and the application of non-invasive ventilation (OR 0.2, 95% CI 0.1-0.5) decreased mortality. No culture of any kind was obtained for 90 (22%) patients during the entire course of the hospitalization. Blood, bronchoalveolar lavage, and non-bronchoscopic lavage cultures yielded enteric Gram-negatives (n=12), followed by Staphylococcus aureus (n=10), pneumococci (n=6), and Pseudomonas aeruginosa (n=6). For 22% of the patients, none of the culture methods were applied. Conclusions: SCAP requiring ICU admission is associated with considerable mortality for ICU patients. Increased awareness appears essential for the microbiological diagnosis of this disease. © 2013 International Society for Infectious Diseases.
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Adult , Aged , Aged, 80 and over , Community-Acquired Infections , Cross Infection , Cross-Sectional Studies , Female , Hospital Mortality , Humans , Intensive Care , Intensive Care Units , Male , Middle Aged , Odds Ratio , Patient Outcome Assessment , Pneumonia , Retrospective Studies , Turkey , Young Adult , CAP , Community-acquired pneumonia , ICU , Intensive care unit , Outcome , adolescent , adult , aged , article , blood culture , community acquired pneumonia , female , Gram negative bacterium , hospitalization , human , hypertension , intensive care unit , lung lavage , major clinical study , male , microbiological examination , mortality , nonhuman , noninvasive ventilation , outcome assessment , Pseudomonas aeruginosa , risk factor , sputum culture , Staphylococcus aureus , Streptococcus pneumoniae , tracheal aspiration procedure , Turkey (republic)