Evaluation of Children with Stenotrophomonas maltophilia Bacteremia; [Stenotrophomonas maltophilia Bakteriyemili Çocuk Olguların Değerlendirilmesi]

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dc.contributor.authorYeşil E.
dc.contributor.authorÇelebi S.
dc.contributor.authorÖzaslan Z.
dc.contributor.authorÖzer A.
dc.contributor.authorKilimci D.D.
dc.contributor.authorHacımustafaoğlu M.
dc.date.accessioned2024-07-22T08:02:48Z
dc.date.available2024-07-22T08:02:48Z
dc.date.issued2023
dc.description.abstractIntroduction: Stenotrophomonas maltophilia (S. maltophilia) is a resistant gram-negative rod that can often cause serious infections, especially in patients with long hospital stays and using broad-spectrum antibiotics. In this study, clinical data, and mortality-related risk factors of patients with S. maltophilia bacteremia were evaluated. Materials and Methods: Patients with S. maltophilia bacteremia included in this study and evaluated retrospectively, when hospitalized between 2013 and 2018 in our pediatric wards and intensive care units. Results: A total of 67 patients had 100 S. maltophilia bacteremia in 70 different episodes. Sixty percent (n=40) of the cases were male and their median age were 9 months. Sixty-nine percent (n=46) of the cases were admitted in intensive care units. The most common comorbidity was malignancy. All bacteremias were healthcare associated, and 55% (n=55) were catheter-related. In the total of 70 episodes; 57% (n=37) of the patients had central venous catheters, 47% (n=33) were entubated. Fourty-seven percent (n=33) of the patients had broad spectrum antibiotic use over 14 days. In the blood cultures, 98% of S. maltophilia-producing strains were sensitive to trimethoprim-sulfamethoxazole. Ciprofloxacin and trimethoprim-sulfamethoxazole combination therapy had used for treatment. The mortality rate in the first 30 days was 16% (n=11). Mechanical ventilation was found to be significant (p<0.05) as a predisposing factor related to mortality. Conclusion: Stenotrophomonas maltophilia is the causative pathogen in healthcare associated bloodstream infections especially in intensive care unit. In our study, 69% of the cases were admitted in the intensive care unit and mechanical ventilation status increased mortality. © 2023, Galenos Publishing House. All rights reserved.
dc.identifier.DOI-ID10.4274/jcp.2023.61482
dc.identifier.issn13049054
dc.identifier.urihttp://akademikarsiv.cbu.edu.tr:4000/handle/123456789/12001
dc.language.isoEnglish
dc.publisherGalenos Publishing House
dc.rightsAll Open Access; Bronze Open Access
dc.subjectaminoglycoside
dc.subjectantibiotic agent
dc.subjectcarbapenem
dc.subjectcephalosporin
dc.subjectcotrimoxazole
dc.subjectglycopeptide
dc.subjectadult
dc.subjectantibiotic sensitivity
dc.subjectArticle
dc.subjectbacteremia
dc.subjectbacterium isolation
dc.subjectbladder catheterization
dc.subjectblood culture
dc.subjectcatheter infection
dc.subjectchild
dc.subjectcomorbidity
dc.subjectcontrolled study
dc.subjectdemographics
dc.subjectevaluation study
dc.subjectfemale
dc.subjecthospitalization
dc.subjecthuman
dc.subjectinfant
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmortality rate
dc.subjectneutropenia
dc.subjectnonhuman
dc.subjectparenteral nutrition
dc.subjectpediatric intensive care unit
dc.subjectpediatric ward
dc.subjectrisk factor
dc.subjectStenotrophomonas maltophilia
dc.titleEvaluation of Children with Stenotrophomonas maltophilia Bacteremia; [Stenotrophomonas maltophilia Bakteriyemili Çocuk Olguların Değerlendirilmesi]
dc.typeArticle

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