Correlations among enthesitis, clinical, radiographic and quality of life parameters in patients with ankylosing spondylitis
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Date
2014
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Abstract
Objectives. To investigate the relationship between enthesitis and disease activity, functional status, fatigue, joint mobility, radiological damage, laboratory parameter and quality of life in patients with ankylosing spondylitis (AS). Methods. A total of 421 patients with AS (323 male and 98 female) who were included in the Turkish League Against Rheumatism Registry were enrolled in the study. The Bath AS Disease Activity Index (BASDAI), fatigue, the Bath AS Functional Index (BASFI), the Bath AS Metrology Index (BASMI), the Maastricht AS Enthesitis Score (MASES), AS quality of life (ASQoL), the Bath AS Radiology Index (BASRI) and erythrocyte sedimentation rate (ESR) were evaluated. Results. Enthesitis was detected in 27.3% of patients. There were positive correlations between MASES and BASDAI, BASFI and fatigue (p < 0.05). MASES was not correlated with BASRI, BASMI, ASQoL and ESR. The mean MASES score was 1.1 ± 2.4. The most frequent regions of enthesopathies were right iliac crest, spinous process of L5 and proximal to the insertion of left achilles tendon, respectively. Conclusions. Enthesitis was found to be associated with higher disease activity, higher fatigue, worse functional status and lower disease duration. As enthesitis was correlated with BASDAI, we conclude that enthesitis can reflect the disease activity in patients with AS. © 2014 Japan College of Rheumatology.
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Keywords
Activities of Daily Living , Adult , Disability Evaluation , Female , Health Status , Humans , Male , Middle Aged , Quality of Life , Questionnaires , Rheumatic Diseases , Severity of Illness Index , Spondylitis, Ankylosing , adult , ankylosing spondylitis , article , Bath ankylosing spondylitis disease activity index , Bath ankylosing spondylitis functional index , body mass , disease activity , disease association , disease duration , enthesitis , erythrocyte sedimentation rate , fatigue , female , functional status , human , joint mobility , major clinical study , male , priority journal , quality of life , radiological parameters , visual analog scale , complication , daily life activity , disability , health status , middle aged , questionnaire , radiography , Rheumatic Diseases , severity of illness index , Spondylitis, Ankylosing